By 22rOn
Published June 18, 2021
The purpose of this series is to explain the connections between the Chinese Communist Party’s virology research programs since 2005 and the research institutions involved, including those in Hong Kong. All information is sourced from the Internet. The analysis and conclusions presented here reflect author’s own views only.
Below is an excerpt from the original report Disclosure Report on CCP’s Virus Research Programs and Projects, edited to fit for online publishing.
In this series, we examine the blueprint of the CCP’s virus research program by focusing on the research program titled Research on Cross-Species Infection and Transmission Mechanism of Major Outbreak of Human-Animal Infections with Animal Origin (hereinafter referred to as the 2016 Virus Program).
With all the information presented in the previous articles, we now conclude this series with a summary, and present the supporting materials.
Conclusion
The CCP has been conducting systematic, organized, and opportunistic virus research for quite a long time. Behind the creation of Covid-19 is the CCP’s virus research program on zoonotic diseases. One example of such research program is the 2016 Virus Program. This program is an extension of director of China CDC, Mr. GAO Fu’s 2005-2015 research project named “Research Project on Mechanisms of Interspecies Infection and Transmission of Viruses of Animal Origin” and “Research Project on Molecular Mechanisms of Pathogenesis of Interspecies Infection and Transmission of Important Viruses”. Wuhan Institute of Virology and PLA’s military medical research institutions are directly involved in these projects. The personnel and funding involved are complex and large, including several military-grade research projects, US NIH, Bill and Melinda Gates Foundation, among other investment agencies. The evidence provided in this report strongly suggests that the CCP’s military is highly likely to have been conducting military-grade biological weapons research at the Wuhan Institute of Virology.
Secondly, in addition to the Wuhan Institute of Virology, it is possible that the CCP authorities have also conducted virus research in other research institutions at the same time. According to the investigation on HKU’s Malik Peiris and GUAN Yi, the CCP very likely has conducted the virus research in Hong Kong and Guangdong, through Shantou University, the newly established Joint Virology Institute of Shantou University and HKU, and the cooperation of Malik Peiris and ZHAO Jincun of Guanzhou Medical University.
COVID-19 may have revealed just a tip of an iceberg of the CCP authorities’ virus research program. According to our investigation, the CCP has various programs under various names, such as the Program 973, the “Infectious Disease Prevention and Control” of National Science and Technology Major Program, to conduct vast, complex and covert national-level virology research programs in a massive and concerted manner, in the course of weaponizing various viruses including Zika, bird flu, Ebola, Dengue, West Nile, and Chikungunya virus. They have conducted large-scale and long-term research on virus analysis and identification, virus transmission and evolution, virus-host interactions, and effective antiviral drugs development studies. Based on the information from our current investigation, the CCP has done the most detailed research on Zika virus and bird flu virus, and those researches have yielded the most results for the CCP authorities. This indicates that the CCP may have altered and weaponized these two viruses, which poses a great risk to the life, health and safety of all mankind.
The CCP has a 20+ year plan to dominate the world. It is being carried out in the name of “One World, One Health” using national-level planning. By following the “Military-Civil Fusion” strategy, CCP scatters its bio-weapon research efforts all across the country to support its CCP virus creation, which is funded by national and local and overseas enterprises and institutions.
If we don’t immediately hold the CCP authorities accountable for their role in the Covid-19 pandemic, it is very likely that more types of man-made deadly virus will imperil mankind again, endlessly wreaking havoc and eroding the entire human civilization.
Annex I 2016 Virus Project Participant List
This table was generated by searching key participants and corresponding authors in the relevant literature, and does not represent a complete list of all personnel. For reference only.
| Project number | Project name | Subject participants | Affiliated units |
| 2016YFD0500300 | Research on Cross-Species Infection and Transmission Mechanism of Major Outbreak of Human-Animal Infections with Animal Origin (parent subject) | Wenjie Tan | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention |
| Yusen Zhou | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences | ||
| Zhendong Zhao | 4. Institute of Pathogen Biology, Chinese Academy of Medical Sciences | ||
| Yi SHI | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention | ||
| Fu GAO | Chinese Center for Disease Control and Prevention | ||
| Hao SONG | Beijing Institute of Life Sciences, Chinese Academy of Sciences | ||
| Sheng CUI | 4. Institute of Pathogen Biology, Chinese Academy of Medical Sciences | ||
| Lilin Zhao | 2. Institute of Zoology, Chinese Academy of Sciences | ||
| Jianghua Sun | 2. Institute of Zoology, Chinese Academy of Sciences | ||
| Guimei He | East China Normal University | ||
| Aihua Zheng | Wuhan Institute of Virology, Chinese Academy of Sciences | ||
| Xiaoqing Lu | Qingdao University | ||
| Guodong Liang | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention | ||
| Hongxuan He | 2. Institute of Zoology, Chinese Academy of Sciences | ||
| Yousong Peng | 17. Hunan University | ||
| Aiping Wu | 9. Suzhou Institute of Systemic Medicine, Chinese Academy of Medical Sciences | ||
| Leiliang Zhang | Shandong First Medical University (Institute of Pathogen Biology, Chinese Academy of Medical Sciences) | ||
| Yuelong Shu | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention | ||
| Dayan Wang | Chinese Center for Disease Control and Prevention | ||
| Taijiao Jiang | 9. Suzhou Institute of Systemic Medicine, Chinese Academy of Medical Sciences | ||
| Haitao Yang | 15. Tianjin University | ||
| Xiaoyun Ji | 14. Changzhou Nanjing University High-Tech Research Institute | ||
| Min FANG | 3. Institute of Microbiology, Chinese Academy of Sciences | ||
| Zhongyang Tan | 17. Hunan University | ||
| YouyangKe | PLA 171 Hospital | ||
| Zhe WANG | 12. Shenyang Agricultural University | ||
| Shuyi Zhang | 12. Shenyang Agricultural University | ||
| Langfeng Wang | Shanghai Pasteur Institute, Chinese Academy of Sciences | ||
| Zefang Wang | 15. Tianjin University | ||
| Houwen Tian | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention | ||
| Li RUAN | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention | ||
| PeihuaNiu | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention | ||
| Xiaoling Shen | Inner Mongolia Medical University | ||
| Jian PENG | 16. Central South University (Xiangya Hospital) | ||
| Jun ZHAO | University of Southern California, USA | ||
| Xia Zanxian | 16. Central South University (Xiangya Hospital) | ||
| Liao Qiande | 16. Central South University (Xiangya Hospital) | ||
| 2016YFD0500301 | Rapid identification, traceability and early warning of major human-animal disease outbreaks and interdiction strategies | Wenjie Tan | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention |
| Fu GAO | Chinese Center for Disease Control and Prevention | ||
| Jincun Zhao | Guangzhou Medical University | ||
| Chuan QIN | 2. Institute of Zoology, Chinese Academy of Sciences | ||
| Songdong Meng | 3. Institute of Microbiology, Chinese Academy of Sciences | ||
| Jianxun Qi | 3. Institute of Microbiology, Chinese Academy of Sciences | ||
| Shixing Tang | Southern Medical University | ||
| Xiaoling Shen | Inner Mongolia Medical University | ||
| Yuelong Shu | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention | ||
| Dayan Wang | Chinese Center for Disease Control and Prevention | ||
| 2016YFD0500302 | Study on the animal origin, evolution and transmission of MERS coronavirus | Yi GUAN | University of Hong Kong |
| Yi GUAN(same) | 10. Shantou University | ||
| Hana M. El Sahly | Baylor College of Medicine, USA | ||
| Guangchuang Yu | Southern Medical University | ||
| 2016YFD0500303 | Study on the natural epidemiological origin and transmission circle of West Nile virus and Chikungunya virus | Jinglin Wang | 8. Yunnan Academy of Animal Husbandry and Veterinary Science |
| 何宏轩 Hongxuan He | 2. Institute of Zoology, Chinese Academy of Sciences | ||
| Chang Yungfu | Cornell University, USA | ||
| Aihua Zheng | Wuhan Institute of Virology, Chinese Academy of Sciences | ||
| Fei YUAN | 3. Institute of Microbiology, Chinese Academy of Sciences | ||
| Dexin Li | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention | ||
| ChangwenKe | Guangdong Center for Disease Control and Prevention | ||
| Mifang Liang | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention | ||
| 2016YFD0500304 | Experimental models of pathogen infection and transmission and studies of adaptive evolution and pathogenicity, hostophilia | Lu LU | Fudan University |
| Shibo Jiang | Fudan University | ||
| Chengfeng Jiang | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences | ||
| Guoyong Yuan | University of Hong Kong | ||
| Lanying Du | New York Blood Center | ||
| Peiyong Shi | University of Texas, USA | ||
| Xiangxi Wang | Institute of Biophysics, Chinese Academy of Sciences | ||
| Yongqiang Deng | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences | ||
| Zhiheng Xu | Institute of Genetics and Developmental Biology, Chinese Academy of Sciences | ||
| Xiaofeng Li | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences | ||
| Ruikang Tang | Zhejiang University | ||
| Genhong Cheng | 9. Suzhou Institute of Systemic Medicine, Chinese Academy of Medical Sciences | ||
| Xiaofeng Qin | 9. Suzhou Institute of Systemic Medicine, Chinese Academy of Medical Sciences | ||
| Chuan QIN | 2. Institute of Zoology, Chinese Academy of Sciences | ||
| Linlin Bao | 2. Institute of Zoology, Chinese Academy of Sciences | ||
| Xianyang Fang | 11. Tsinghua University | ||
| Zihe Rao | 11. Tsinghua University | ||
| David I. Stuart | University of Oxford | ||
| Jianghong Man | National Center for Biomedical Analysis | ||
| Bo ZHANG | Wuhan Institute of Virology, Chinese Academy of Sciences | ||
| Leiliang Zhang | Shandong First Medical University (Institute of Pathogen Biology, Chinese Academy of Medical Sciences) | ||
| Wenjie Tan | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention | ||
| Chuan QIN | 2. Institute of Zoology, Chinese Academy of Sciences | ||
| Songdong Meng | 3. Institute of Microbiology, Chinese Academy of Sciences | ||
| Jincun Zhao | Guangzhou Medical University | ||
| 2016YFD0500305 | Important protein structural analysis for pathogen-host interactions | Fu GAO | Chinese Center for Disease Control and Prevention |
| Jianxun Qi | 3. Institute of Microbiology, Chinese Academy of Sciences | ||
| Feng GAO | Tianjin Industrial Biotechnology Research Institute | ||
| Wenjie Tan | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention | ||
| Chuan QIN | 2. Institute of Zoology, Chinese Academy of Sciences | ||
| Songdong Meng | 3. Institute of Microbiology, Chinese Academy of Sciences | ||
| Jincun Zhao | Guangzhou Medical University | ||
| Jinhai Huang | 15. Tianjin University | ||
| 2016YFD0500306 | Study on the evolutionary development of immunity and immune recognition characteristics of different species of animals against pathogens | Yusen Zhou | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences |
| Shibo Jiang | Fudan University | ||
| Lanying Du | New York Blood Center | ||
| Fang LI | University of Minnesota, USA | ||
| Enqi Du | 13. Northwest Agriculture and Forestry University | ||
| Suresh K. Tikoo | University of Saskatchewan, Canada | ||
| Xiaoying Zhang | 13. Northwest Agriculture and Forestry University | ||
| Linqi Zhang | 11. Tsinghua University | ||
| Xinquan Wang | 11. Tsinghua University | ||
| Sha PENG | 13. Northwest Agriculture and Forestry University | ||
| Jinlian Hua | 13. Northwest Agriculture and Forestry University | ||
| 2016YFD0500307 | Mechanisms of important pathogen-host immune system interactions and cross-species transmission | Shan CEN | 6. Institute of Pharmaceutical Biotechnology, Chinese Academy of Medical Sciences |
| Xiaoyu Li | 6. Institute of Pharmaceutical Biotechnology, Chinese Academy of Medical Sciences | ||
| Mei GE | Shanghai Jiao Tong University | ||
| Yusen Zhou | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences | ||
| Shibo Jiang | Fudan University | ||
| Lanying Du | New York Blood Center | ||
| Shihui Sun | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences(Institute of Biological Engineering, PLA Academy of Military Medical Sciences) | ||
| Guangyu Zhao | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences | ||
| Yan GUO | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences | ||
| Yuehong Chen | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences | ||
| Junfeng Li | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences | ||
| Xinquan Wang | 11. Tsinghua University | ||
| Ye XIANG | 11. Tsinghua University | ||
| Chen LIANG | McGill University, Canada | ||
| Chengfeng Qin | 7. Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences | ||
| Fei GUO | 6. Institute of Pharmaceutical Biotechnology, Chinese Academy of Medical Sciences | ||
| Linqi Zhang | 11. Tsinghua University | ||
| Xinquan Wang | 11. Tsinghua University | ||
| Baoluo Zhou | Shanghai Pasteur Institute, Chinese Academy of Sciences | ||
| Mifang Liang | 1. Institute of Viral Disease Prevention and Control, Chinese Center for Disease Control and Prevention |
Annex II Funding Information of the 2016 Virus Program
This table is a summary of search results, which include all the projects and funding information of the 2016 Virus Program by December 2019. The Chinese name of some researchers could not be found.
| 2016 Virus Program/Project No. | Paper Title | Publication Date (online) Year/Month | Authors | Other Funding Support | Note | |
| 2016YFD0500300 | Homologous recombination shapes the genetic diversity of African swine | August, 2019 | Zhaozhong Zhu, Chao-Ting Xiao, Yunshi Fan, Zena Cai, Congyu Lu, Gaihua Zhang, Taijiao Jiang, Yongjun Tan, Yousong Peng* | The National Key Technology R&D Program of China (2017YFD0500104), National Natural Science Foundation of China (31671371), Chinese Academy of Medical Sciences (CAMS) Innovation Fund (2016-12M-1-005), Natural Science Foundation of Hunan Province (2018JJ3039) | – | |
| 2016YFD0500300 | Analysis of Microsatellite Distribution in Complete Ebolavirus Genomes | March, 2019 | Siqian Zhou, Weili Jiao, Zhuli Peng, Jingyu Zhou, Xingxin He, Durui Li, Mingfu Li, Zhongyang Tan* | The National Key Technology R&D Program of China (2016YFC1200200), Research and application of inspection and control technology for massive cross-border biological species (2017YFF0210300), Big data platform and assessment and early warning system for massive cross-border species (2017YFF0210301) | – | |
| 2016YFD0500300 | The biological function of guanylate binding protein 2 | May, 2019 | Jinhong Tang, Haitao Yang, Zefang Wang* | 973 Program (2014CB542800, 2015CB859800), National Natural Science Foundation of China (31528006) | – | |
| 2016YFD0500300 | A novel human mAb (MERS-GD27) provides prophylactic and postexposure efficacy in MERS-CoV susceptible mice | July, 2018 | PeihuaNiu, Guangyu Zhao, Yao Deng, Shihui Sun, Wenling Wang, Yusen Zhou*, Wenjie Tan* | – | Wenjie Tan and L. Haagmans and Ron A.M. of Erasmus MC in Rotterdam, Zuid-Holland also contributed to this work. | |
| 2016YFD0500300 | Contribution of intertwined loop to membrane association revealed by Zika virus full-length NS1 structure | August, 2016 | Xiaoying Xu, Hao Song, Jianxun Qi, Yuqian Liu, Haiyuan Wang, Chao Su, Yi SI*, Fu GAO* | China Ministry of Science and Technology National 973 Project Grant (2014CB542503), National Natural Science Foundation of China (81641001, 81622031), the Emergency Task-Force Project of Zika Virus Research, The Strategic Priority Research Program of the Chinese Academy of Sciences (XDB08020100), Chinese Academy of Sciences (CAS) Youth Innovation Promotion Association (2015078) | Partially funded by the National Natural Science Foundation of China Innovation Research Group 81321063, led by Fu Gao. | |
| 2016YFD0500300 | Crystal structure of the C-terminal fragment of NS1 protein from yellow fever virus | November, 2017 | Haiyuan Wang, Min Han, Jianxun Qi, Rolf Hilgenfeld, Tingrong Luo, Yi Shi, Fu GAO*, Hao Song* | National Science and Technology Major Project (2017ZX10303403), National Natural Science Foundation of China (2016QNRC001), Chinese Academy of Sciences (CAS) Youth Innovation Promotion Association 2015078 and (2017117). | Partially funded by the National Natural Science Foundation of China Innovation Research Group 81621091, led by Fu Gao. | |
| 2016YFD0500300 | From discovery to spread: The evolution and phylogeny of Getah virus | November, 2017 | Yuan-Yuan Li, Hong Liu, Shihong Fu, Xiaolong Li, Xiaofang Guo, Minghua Li, Yun Feng, Wei-Xin Chen, Li-Hua Wang, Wenwen Lei, Xiaoyan Gao, ZhiLyu, Ying He, Huanyu Wang, Hongning Zhou, Gui-Qin Wang* Guodong Liang* | The National Key Research and Development Program of China (2016YFC120190), State Key Laboratory of Infectious Disease Prevention and Control (SKLID) (2014SKLID103, 2015SKLID505), The Open Research Fund Program of the Chinese Academy of Sciences Wuhan National Biosafety Level-4 Laboratory (2017SPCAS003) | ||
| 2016YFD0500300 | Genome sequencing and phylogenetic analysis of Banna virus (genus Seadornavirus, family Reoviridae) isolated from Culicoides | October, 2017 | Song Song, Yuanyuan Li, Shihong Fu, Wenwen Lei, Xiaofang Guo, Yun Feng, Xiaoyan Gao, Xiaolong Li, Zhonghua Yang, Ziqian Xu, Ying He, Huanyu Wang, Hongning Zhou, Bin Wang, Xiaoqing Lu*, Guodong Liang* | The National Key Research and Development Program of China (2016YFC1201904), National Natural Science Foundation of China (81290342, 81501757 [Special Science Fund]); State Key Laboratory of Infectious Disease Prevention and Control (2014SKLID103, 2015SKLID505). | ||
| 2016YFD0500300 | Natural killer cells are activated and play a protective role against ZIKA virus infection in mice | July, 2017 | Xuefeng Duan, Shihua Li, GaryWong, Dongfang Wang, Haoyu Wang, Jiao Lu, Yuhai Bia, Xuancheng Lu, Yi Shi, Jinghua Yan, Min Fang*, George Fu Gao* | China Ministry of Science and Technology National 973 Project Grant (2015CB910503, 2014CB542602), National Natural Science Foundation of China (31370877, 31322020, 31400151), Emergency Task-Force Project of Zika Virus Research (KJZDEW-L15). | Min Fang was supported by “The Recruitment Program of Global Experts”; Songji Wang was supported by the Banting Postdoctoral Fellowships of the Canadian Institutes of Health Research. | |
| 2016YFD0500300 | Significant Spike-Specific IgG and Neutralizing Antibodies in Mice Induced by a Novel Chimeric Virus-Like Particle Vaccine Candidate for Middle East Respiratory Syndrome Coronavirus | October, 2018 | Jiaming Lan, Yao Deng, Kingdong Song, Baoying Huang, Wenling Wang, Wenjie Tan* | Infectious Disease Control S&T Grand Project (2014ZX10004001-002, 2016ZX10004001-003), The National Key Research and Development Program of China (2016YFC1200901, 2016YFC1200200). | Copyright belongs to Wuhan Institute of Virology | |
| 2016YFD0500300 | West Nile virus infection in suspected febrile typhoid cases in Xinjiang, China | July, 2017 | Lei Cao, Shihong Fu, ZhiLyu, Chengjun Tang, Shiheng Cui, Xiaolong Li, Xiaoyan Gao, Minghua Li, Yuxi Cao, Wenwen Lei, Ying He, HuanyuWang, Guodong Liang* | The National Key Research and Development Program of China (2016YFC1201900), National Natural Science Foundation of China (81290342, 81501757), State Key Laboratory of Infectious Disease Prevention and Control, SKLID, China CDC (2014 SKLID103,2015SKLID505) | – | |
| 2016YFD0500300 | ZIKA virus isolated from mosquitoes： a field and laboratory investigation in China, 2016 | October, 2017 | Shihong Fu, Song Song, Hong Li, Yuanyuan Li, Xiaolong Li, Xiaoyan Gao, Ziqian Xu, Guoping Liu, Dingming Wang, Zhenzhao Tian, Jingzhu Zhou, Ying He, Wenwen Lei, Huanyu Wang, Bing Wang, Xiaoqing Lu*, Guodong Liang* | The National Key Research and Development Program of China (2016YFC1201904, 2017YFC1200202), National Natural Science Foundation of China (81290342, 81501757 [the Special National Project]), The Open Research Fund Program of the Chinese Academy of Sciences Wuhan National Biosafety Level-4 Laboratory (2017SPCAS003). | The Chinese Academy of Sciences Wuhan National Biosafety Level-4 Laboratory was involved in this research | |
| 2016YFD0500300 | Preparation and characteristic analysis of six influenza A (H7N9) pseudovirus derived from different districts of China | August, 2017 | Baoying Huang, Shanqin Li, Xiangrong Qi, Jiao Ren, Jingdong Song, Wenjie Tan, Houwen Tian* & Li Ruan* | National Infectious Disease Control S&T Grand Project (2014ZX10004002), 863 Program (2016AA02A203), National Natural Science Foundation of China (31200127), The National Key Research and Development Program of China (2016YFC1200200). | – | |
| 2016YFD0500300 | Performance evaluation of a novel automatic nucleic acid extraction method for detection of pathogens | May, 2019 | Liyuan Zhu, Wenjia Ye, Funa Lu, Jiaoxue Tang, Xiaokai Xia, PeihuaNiu, Wenjie Tan* | The National Key Research and Development Program of China (2016YFC1200900). | – | |
| 2016YFD0500300 | Recent Advances in Novel Vaccines Development against Zika Virus | November, 2017 | Ying Zhan, Yao Deng, Wenjie Tan* | National Infectious Disease Control S&T Grand Project (2016ZX10004001-003). | – | |
| 2016YFD0500300 | Progress in development of neutralizing monoclonal antibody （ McAb ） against MERS-CoV | September, 2017 | Yingzhu Chen, Kun Qin, Wenjie Tan* | The National Key Research and Development Program of China (2016YFC1200900), National Infectious Disease Control S&T Grand Project (2016ZX10004001-003). | – | |
| 2016YFD0500300 | Research progress in the serological detection of coronavirus（CoV）for the Middle East respiratory syndrome（MERS-CoV） | May, 2018 | Miaomiao Ma, Xiaoling Shen, Wenjie Tan* | The National Key Research and Development Program of China (2016YFC1200900), National Infectious Disease Control S&T Grand Project (2016ZX10004001-003). | – | |
| 2016YFD0500300 | Isolation and Identification of the Nam Dinh Virus from Mosquitoes on the China-Laos-Myanmar Border | November, 2016 | Wenwen Lei, Xiaofang Guo, Shihong Fu, Yun Feng, Jingdong Song, Hongning Zhou, Guodong Liang* | National Natural Science Foundation of China (81290342 [Special Science Fund]), State Key Laboratory of Infectious Disease Prevention and Control (2014SKLID103) | – | |
| 2016YFD0500300 | Effects of calcitriol (1, 25-dihydroxy-vitamin D3) on the inflammatory response induced by H9N2 influenza virus infection in human lung A549 epithelial cells and in mice | January, 2017 | BoxiangGui, Qin Chen, Chuanxia Hu, Caihui Zhu, Guimei He* | National Natural Science Foundation of China (31402163), Shanghai Municipal Center for Disease Control & Prevention | – | |
| 2016YFD0500300 | Intraviral interactome of Chikungunya virus reveals the homo-oligomerization and palmitoylation of structural protein TF | April, 2019 | Han Yin, Peiqi Yin, Hongjian Zhao, Na Zhang, Xia Jian, Siqi Song, Shan Gao, Leiliang Zhang* | National Natural Science Foundation of China (81871663, 81672035), Shandong Provincial Natural Science Foundation (ZR2017PC017). | Dr. Andres Merits and Dr. Terence Dermody provided reagents. | |
| 2016YFD0500300 | Retromer localizes to autophagosomes during HCV replication | April, 2017 | Peiqi Yin, Zhi Hong, Leiliang Zhang*, YouyangKe* | National Natural Science Foundation of China (81471955, 81672035, 81301438), the Program for Changjiang Scholars and Innovative Research Team in Universities (IRT13007), Fundamental Research Funds for the Central Universities (3332016085). | GuangboYangcontributed to this research；Charles Rice, Francis Chisari,ZhipingXie, Masanori Ikeda, Nobuyuki Kato and TakajiWakita provided reagents. | |
| 2016YFD0500300 | Sec24C – Dependent Transport of Claudin -1 Regulates Hepatitis C Virus Entry | August, 2017 | Peiqi Yin, Ye Li, Leiliang Zhang* | National Natural Science Foundation of China (81672035, 81471955), Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (2016-12M-3-020), Fundamental Research Funds for the Central Universities (3332013118, 2016ZX310047), the Program for Changjiang Scholars and Innovative Research Team in Universities (IRT13007). | Charles Rice, Francis Chisari, Xiaowei Chen, Sidney Yu and Ping Zhao provided reagents. | |
| 2016YFD0500300 | Entry of severe fever with thrombocytopenia syndrome virus | December, 2016 | Fei Yuan, Aihua Zheng* | National Natural Science Foundation of China (L1524009), the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB11030800). | Wuhan Institute of Virology hosted this research. | |
| 2016YFD0500300 | Development and validation of a novel 13-plex PCR system for commonly used short tandem repeats in horses (Equus caballus) | September, 2019 | S. Shang, M. Zhang, Y. Zhao, W. Dang, P. Hua, S. Zhang*, Z. Wang* | The National Key Research and Development Program of China (2016YFC1200100), National Natural Science Foundation of China (31672274,31570382). | – | |
| 2016YFD0500300 | Molecular signatures and functional analysis of beige adipocytes induced from in vivo intra-abdominal adipocytes | July, 2018 | HuilingXue, Zhe Wang, Yongjie Hua, Shanshan Ke, Yao Wang, JunpengZhang,Yi-Hsuan Pan, Wenjie Huang, David M. Irwin, Shuyi Zhang* | The National Key Research and Development Program of China (2016YFC1200100), National Natural Science Foundation of China (31672274,31570382). | – | |
| 2016YFD0500300 | Retention and losses of ultraviolet-sensitive visual pigments in bats | August, 2018 | Longfei Li, Hai Chi, Haonan Liu, Yu Xia, David M. Irwin, Shuyi Zhang*, Yang Liu* | The National Key Research and Development Program of China (2016YFC1200100), National Natural Science Foundation of China (31601855,31570382). | YimengCui,Dr. Rosalie K. Crouch, Dr. Lisa A. Neuhold | |
| 2016YFD0500300 | Synergy between MC1R and ASIP for coat color in horses (Equus caballus) | February, 2019 | Songyang Shang, Yan Yu, Wanyi Dang, Yuxin Zhao, Junpeng Zhang, Xia Qin, David M. Irwin, Qin Wang, Fei Liu, Zhenshan Wang, Shuyi Zhang*, Zhe Wang* | The National Key Research and Development Program of China (2016YFC1200100), National Natural Science Foundation of China (31672274,31570382). | – | |
| 2016YFD0500300 | Identification of Bridging Centrality in Complex Networks | July, 2019 | Wei Liu, Matteo Pellegrini, Aiping Wu* | National Natural Science Foundation of China (31470213), Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (2016-12M-1-005), Jiangsu Provincial Natural Science Foundation (BK2016245), Shandong Provincial Natural Science Foundation (ZR2017MF052), Ludong University (LA2016007) | – | |
| 2016YFD0500300 | Large discrepancy between the two-way rNHT distances in hemagglutinin-inhibition assay | August, 2016 | Yousong Peng, Dayan Wang, Yuelong Shu*, Taijiao Jiang* | The National Key Research and Development Program of China (2016YFC1200200), National Natural Science Foundation of China (31500126, 31371338), Hunan University Young Faculty Growth Program (31107040720). | – | |
| 2016YFD0500300 | PREDAV-H1-a user-friendly web server for predicting antigenic variants of influenza H1N1 viruses | October, 2018 | Congyu Lu, Mi Liu, Aiping Wu, Yuelong Shu, Yousong Peng*, Taijiao Jiang* | The National Key Research and Development Program of China (2016YFC1200200), National Natural Science Foundation of China (31500126, 31671371), Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (2016-12M-1-005), Fundamental Research Funds for the Central Universities. | – | |
| 2016YFD0500300 | Michael Acceptor-Based Peptidomimetic Inhibitor of Main Protease from Porcine Epidemic Diarrhea Virus | March, 2017 | Fenghua Wang, Cheng Chen, Kailin Yang, Yang Xu, Xiaomei Liu, Fan Gao, He Liu, Xia Chen, Qi Zhao, Xiang Liu, Yan Cai*, Haitao Yang* | China Ministry of Science and Technology National 973 Project Grant (2015CB859800), National Natural Science Foundation of China (31528006), Tianjin Marine Science and Technology Program (KJXH2014-16). | – | |
| 2016YFD0500300 | The conformational changes of Zika virus methyltransferase upon converting SAM to SAH | January, 2017 | Han Zhou, Fenghua Wang, Haofeng Wang, Cheng Chen, Tianqing Zhang, Xu Han, Deping Wang, Chen Chen, Chen Wu, Wei Xie, 王泽方, Lei Zhang, Lanfeng Wang*, Haitao Yang* | China Ministry of Science and Technology National 973 Project Grant (2015CB859800), National Natural Science Foundation of China (31528006), and the start-up funds from Institute Pasteur of Shanghai, Chinese Academy of Sciences | Institute Pasteur of Shanghai was involved in this research. | |
| 2016YFD0500300 | A Novel DT40 Antibody Library for the Generation of Monoclonal Antibodies | June, 2019 | Bei Wang, Fei Wang, He Huang*, Zhendong Zhao* | The Project of the National Defense Science and Technology Innovation Special Zone (17-163-12-ZT-005-013-01), Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (2016-12M-1-013, 2016-12M-1-014, 2016-12M-3-020), Fundamental Research Funds for the Central Universities (2018PT31032). | This research is directly related to PLA research projects; the copyright was held by Wuhan Institute of Virology. | |
| 2016YFD0500300 | Crystal structure of Middle East respiratory syndrome coronavirus helicase | June, 2017 | Wei Hao, Justyna Aleksandra Wojdyla, Rong Zhao, Ruiyun Han, Rajat Das, Ivan Zlatev, Muthiah Manoharan, Meitian Wang, Sheng Cui* | National Natural Science Foundation of China (81501759, 81572005). | Hongjie Zhang (Core Facility for Protein Research, Institute of Biophysics, Chinese Academy of Sciences) was involved in this research. | |
| 2016YFD0500300 | Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication | October, 2017 | Tao Wang, Bei Wang, He Huang, Chongyang Zhang, Yuanmei Zhu, Bin Pei, Chaofei Cheng, Lei Sun, Jianwei Wang, Qi Jin, Zhendong Zhao | National Natural Science Foundation of China (81572008, 31400159), Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (2016-12M-1-014), the Innovative Research Team in University (IRT13007) | – | |
| 2016YFD0500300 | Structural characterization of free-state and product-state Mycobacterium tuberculosis methionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism | June, 2018 | Wei Wang, Bo Qin, Justyna Aleksandra Wojdyla, Meitian Wang, Xiaopan Gao*, Sheng Cui* | National Natural Science Foundation of China (11775308, 81401714), Fundamental Research Funds for the Central Universities (2016ZX310054), China Academy of Chinese Medical Sciences grants (2017PT31049, 2017-12M-3-014), Natural Science Foundation of Beijing Municipality grants (7182117, 77174288). | – | |
| 2016YFD0500300 | Transduction with Lentiviral Vectors Altered the Expression Profile of Host MicroRNAs | July, 2018 | He Huang, Chongyang Zhang, Bei Wang, Fei Wang, Bin Pei, Chaofei Cheng, Wei Yang, Zhendong Zhao* | National Natural Science Foundation of China (81301440), Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (016-12M-1-013, 2016-12M-1-014), Fundamental Research Funds for the Central Universities (3332014026, 2017PT31010). | – | |
| 2016YFD0500300 | Differential immune responses of Monochamusalternatus against symbiotic and entomopathogenic fungi | July, 2017 | Wei Zhang, Jie Meng, Jing Ning, Peijun Qin, Jiao Zhou, Zhen Zou, Yanhong Wang, Hong Jiang, Faheem Ahmad, Lilin Zhao*, Jianghua Sun* | The National Key Research and Development Program of China (2016YFC1200604), The High Technology Research and Development Program (HTRDP) of China (2014AA020529), National Natural Science Foundation of China (31572272, 31370650, 31402013, 31221091, 31672291, L1524009), The Forestry Industry Research Special Funds for Public Welfare Program (201204501), The CAS Key Research Projects of the Frontier Science (QYZDB) (QYZDBSSW-SMC014), Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (2015-SM-C-02). | – | |
| 2016YFD0500300 | HA Triggers the Switch from MEK1 SUMOylation to Phosphorylation of the ERK Pathway in Influenza A Virus-Infected Cells and Facilitates Its Infection | February, 2017 | Chengmin Wang, Huimin Liu, Jing Luo, Lin Chen, Meng Li, Wen Su, Na Zhao, Shelan Liu, Li Xie, Yaxiong Jia, Hua Ding, Xiufeng Wan, Hongxuan He* | National major research and development projects (2016YFD0500300), China Agriculture Research System Poultry-related Science and Technology Innovation Team of Peking (CARS-PSTP). | China Agriculture Research System Poultry-related Science and Technology Innovation Team of Peking (CARS-PSTP) contributed to this research. | |
| 2016YFD0500300 | Histone Deacetylase 1 Plays an Acetylation-Independent Role in Influenza A Virus Replication | December, 2017 | Lin Chen, Chengmin Wang, Jing Luo, Wen Su, Meng Li, Na Zhao, WentingLyu, Hamidreza Attaran, Yapeng He, Hua Ding, Hongxuan He* | The key study program of the National Natural Science Foundation of China (No. 81101835), the Chinese Academy of Sciences (KSZD-EW-Z-005-001-1), National key plan for Scientific and Development of China (2016YFD0500300), China Agriculture Research System Poultry-related Science and Technology Innovation Team of Peking (CARS-PSTP) | Wanqin Liao, Xiaoling Li, Ting Han, Qingxun Zhang, Zhirong Shen and Lv Lu also contributed to this research. | |
| 2016YFD0500300 | Mcl-1 suppresses abasic site repair following bile acid–induced hepatic cellular DNA damage | July, 2017 | Haiyang Yu, Xiaoqing Zhang, Ren Liu, Hui Li, Xiaolong Xiao, Yuzheng Zhou, Chaoying Wei, Manyi Yang, Mingmei Liao, Jinfeng Zhao, Zanxian Xia, Qiande Liao | National Natural Science Foundation of China (81272193, 81302075, 81402001, and U1603126), the National Key Research and Development Program of China (2016YFD0500300). | – | |
| 2016YFD0500300 | Regulation of WNT_β-catenin signaling by carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD) in colorectal cancer cell | December, 2017 | Chengming Ding, Jun He, Wenyan Liao, Jie Chen, Junhua Li, Gengsheng He, Zeming Jia, Yaoting Zhang, Jiaxing Luo, Xiaoming Dai, Liming Zhang, Hui Li, Yuzheng Zhou, Ai Lu, Zanxian Xia, Jun Zhao, Jian Peng | The National Key Research and Development Program of China (2016YFC12- 00200), the National Natural Science Foundation of China (U1603126), Hunan Provincial Natural Science Fund in China (2017JJ2334). | Pinghui Feng (University of Southern California), Chengyu Liang (University of Southern California) also contributed to this research | |
| 2016YFD0500301 | Epidemic and molecular characteristic of human adenovirus infection among patients with febrile respiratory syndrome from a hospital in Qinghai Province, 2012-2015 | July, 2017 | Hong Li, Gaoshan Liu, Yan Shi, PeihuaNiu, Shuangying Jiang, Lili Xu, Roujian Lu, Shengcang Zhao*, Wenfie Tan* | National Infectious Disease Control S&T Grand Project (2013ZX10004-601, 2014ZX10004-001, 2012ZX10004-208). | – | |
| 2016YFD0500301 | Comparison of viral and epidemiologicalprofiles of hospitalized children with severeacute respiratory infection in Beijing and Shanghai, China | August, 2018 | Yanjie Zhao, Roujian Lu, Jun Shen, ZhengdeXie, Gaoshan Liu, Wenjie Tan* | The National Key Research and Development Program of China (2016YFC1200200), National Infectious Disease Control S&T Grand Project (2014ZX10004001–002, 2017ZX10104001–002, 2017ZX10104001–003). | – | |
| 2016YFD0500301 | Humoral and cellular immunity against both ZIKV and poxvirus is elicited by a two-dose regimen using DNA and non-replicating vaccinia virus-based vaccine candidates | March, 2019 | Ying Zhan, Yao Deng Baoying Huang, Qianqian Song, Wen Wang, Yang Yang, Lianpan Dai, WenlingWang, Jinghua Yan, Gorge F Gao, Wenjie Tan* | The National Key Research and Development Program of China (2016YFC1200200, 2016YFC1200901), National Infectious Disease Control S&T Grand Project (2016ZX10004001-003). | – | |
| 2016YFD0500301 | Molecular Evidence of Human Monkeypox Virus Infection, Sierra Leone | June, 2019 | Fei Ye, Jingdong Song, Li Zhao, Yi Zhang, Lianxu Xia, Lingwei Zhu, Idrissa Laybohr Kamara, Jiao Ren, Wenling Wang, Houwen Tian, Guizhen Wu, Wenjie Tan | The National Key Research and Development Program of China (2016YFC1200200, 2016YFC1200905), National Infectious Disease Control S&T Grand Project (2016ZX10004222-002). | – | |
| 2016YFD0500301 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus–Derived CD8+ T Cell Epitopes and Host MHC | November, 2016 | William J Liu, Jiaming Lan, Kefang Liu, Yao Deng, Yanfeng Yao, Shaolian Wu, Hong Chen, Lingling Bao, Haifeng Zhang, Min Zhao, Qihui Wang, Lingxia Han, Yan Chai, Jianxun Qi, Jincun Zhao, Songdong Meng, Chuan Qin, Fu GAO, Wenjie Tan | China Ministry of Science and Technology National 973 Project Grant (2015CB910500), National Infectious Disease Control S&T Grand Project (2016ZX10004222-003, 2014ZX10004001-002, 2014ZX10004001-006, 2012ZX10004501-004), National Natural Science Foundation of China (81373141, 81401312, 81461168030), Municipal Healthcare Joint Innovation Major Project of Guangzhou Grant (201604020011) | Bart L. Haagmans and Ron A. M. Fouchier (Erasmus MC, Rotterdam, the Netherlands) for providing MERS-CoV (isolate hCoV-EMC/2012); Stanley Perlman (University of Iowa, Iowa City, IA) for providing the rAd5-hDPP4 stock; Jianfang Zhou (National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention) for assistance on the flow cytometry. | |
| 2016YFD0500301 | Safe and Sensitive Antiviral Screening Platform Based on RecombinantHuman Coronavirus OC43 Expressing the Luciferase Reporter Gene | July, 2016 | Liang Shen, Yang Yang, Fei Ye, Gaoshan Liu, Marc Desforges, Pierre J Talbot, Wenjie Tan | National Infectious Disease Control S&T Grand Project (2014ZX10004001, 2013ZX10004601). | – | |
| 2016YFD0500301 | Viral and Bacterial Etiology of Acute Febrile Respiratory Syndrome among Patients in Qinghai, China | June, 2019 | Gao Shan Liu, Hong Li, Sheng Cang Zhao, Rou Jian Lu, Pei Hua Niu*, Wen Jie Tan* | The National Key Research and Development Program of China (2016YFC1200200), National Infectious Disease Control S&T Grand Project (2017ZX10104001-002-003, 2014ZX10004001-002). | The CDC of Qinghai also contributed to this research. | |
| 2016YFD0500301 | Development and application of novel techniques for viral isolation and culture | March, 2017 | Bing-jie Wu, Rou-jian Lu, Wen-jie Tan* | National Natural Science Foundation of China (81100062). | – | |
| 2016YFD0500301 | Confirmation of one human Monkeypox infection in Sierra Leone in 2017 by molecular and serological detection | June, 2019 | Fei Ye, Jing-dong Song, Li Zhao, Yi Zhang, Lian-xu Xia, Ling-wei Zhu, Jiao Ren, Wen-ling Wang, Gui-zhen Wu, Hou-wen Tian*, Wen-jie Tan* | National Infectious Disease Control S&T Grand Project (2016ZX10004222-002). | – | |
| U72016YFD0500301 | Study on the Cell Biological Properties and Replication Defective Mechanism of Replication-deficient Vaccinia Virus Titan Strain | 2January 2019 | ZHAO Ying, HUANG Pan, ZHAO Li, REN Jiao, ZHANG Peng, RUAN Li, TAN Wenjie, TIAN Houwen* | – | – | |
| 2016YFD0500301 | Establishment of an ELISA Assay for Serum Antibodies to Monkeypox Virus Infection | December 2018 | REN Jiao, YE Fei, ZHAO Li, GUAN Xixi, ZHAO Ying, SONG Jingdong, TIAN Houwen, TAN Wenjie* | – | – | |
| 2016YFD0500301 | Titration and Neutralizing Antibody Detection of Middle East Respiratory Syndrome Coronavirus Infection Based on Avicel-crystalline Violet Staining of Empty Spots | January 2017 | WANG Wenling, HUANG Baoying, WANG Huijuan, ZHAO Li, LU Roujian, ZHU Na, DENG Yao, TAN Wenjie* | National Science and Technology Major Project for the Control and Prevention of Major Infectious Diseases 2016ZX10004001 | – | |
| 2016YFD0500301 | Rapid Establishment of a Mouse Model of MERS-CoVPseudovirus Infection Based on DPP4 Transduction | April 2019 | NIU Junwei, ZHAN Ying, DENG Yao, TAN Wenjie* | National Science and Technology Major Project for the Control and Prevention of Major Infectious Diseases 2016ZX10004001-003 | – | |
| 2016YFD0500301 | New Technology and Preliminary Application of Neutralizing Antibody Detection Based on Rabies Virus CVS-11 Pseudovirus | October 2016 | DENG Yao, LvXinjun, YU Pengcheng, XU Honglin, TANG Qing, ZHU Wuyang, TAN Wenjie* | “863” Program 2014AA021406 | – | |
| 2016YFD0500301 | New Technology and Preliminary Application of Neutralizing Antibody Detection Based on Rabies Virus CVS-11 Pseudovirus | October 2019 | WANG Wenling, YANG Ren, SONG Qianqian, WANG Huijuan, DENG Yao, ZHAO Li, TAN Wenjie* | 863 Program 2014AA021406, National Key R&D Program 2016YFC1200900, National Science and Technology Key Projects on Infectious Disease Prevention and Control 2016ZX10004001-003 | – | |
| 2016YFD0500301 | Detection of Zika Virus Antibodies by Luciferase Immunosorbent Assay Based on Zika Virus NS2B Protein-Specific Antigenic Polypeptides | May 2019 | WANG Tianyu, WU Wei, DENG Yao, WANG Wenling, TAN Wenjie*, TANG Shixing* | National Key R&D Program 2016YFC1200900, National Science and Technology Major Project on Infectious Disease Prevention and Control 2016ZX10004001-003 | Southern Medical University | |
| 2016YFD0500301 | Enhanced Virulence of Influenza A Virus X31 (H3N2) Mice after Adaptation is Associated with HA and PB2 Mutations | November 2019 | LU Funa, WANG Wenling, ZHANG Yawei, TONG Yigang, LIU Kefang, HUANG Baoying, SHEN Xiaoling, TAN Wenjie* | National Natural Science Foundation of China 31200127 | – | |
| 2016YFD0500301 | Efficient Screening of Human Coronavirus OC43 Susceptible Cell Lines | May 2017 | SHEN Liang, ZHU Na, NIU Junwei, HUANG Baoying, LIU Gaoshan, NIU Peihua, TAN Wenjie* | National Key R&D Programm 2016YFC1200200, 2016YFC1200905 | – | |
| 2016YFD0500301 | Advances in Human Anellovirus Virus Research | January 2018 | LIU Gaoshan, NIU Junwei, TAN Wenjie* | – | – | |
| 2016YFD0500301 | Advances in the Antiviral Effects and Mechanisms of Emetine | NIU Junwei, TAN Wenjie* | – | – | ||
| 2016YFD0500301 | Application of Primary Human Airway Epithelial (HAE) Cells for Isolation and Identification of Influenza Virus in Aged Airway Samples | May 2017 | ZHU Na, WEI Hejiang, SONG Jingdong, NIU Peihua, WANG Wen, WANG Dayan, SHU Yuelong, TAN Wenjie* | National Science and Technology Major Project for Infectious Disease Control 2014ZX10001004-001, 2014ZX10001004-002, National Natural Science Foundation of China 81301430 | – | |
| 2016YFD0500301 | Primary Human Airway Epithelial (HAE) Cell Culture System and its Application in Virology Research | April 2017 | ZHU Na, TAN Wenjie* | National Science and Technology Major Project for Infectious Disease Control 2014ZX10001004-001, 2014ZX10001004-002, National Natural Science Foundation of China 81301430 | – | |
| 2016YFD0500301 | Advances in Serological Detection Methods for Zika Virus | May 2019 | WANG Tianyu, TANG Shixing*, TAN Wenjie* | National Key R&D Program 2016YFC1200900, National Major Project on Science and Technology for Infectious Disease Control 2016ZX10004001-003 | Southern Medical University participated in the study | |
| 2016YFD0500301 | Study on Optimization of Signal Peptide Sequences for Eukaryotic Expression of MERS-CoV Spiked Protein Subunits | January 2019 | SONG Qianqian, WANG Wenling, ZHAN Ying, LU Funa, DENG Yao, TAN Wenjie* | National Key R&D Program 2016YFC1200900, National Science and Technology Major Project for the Control and Prevention of Major Infectious Diseases 2016ZX10004001-003 | – | |
| 2016YFD0500302 | A field‐deployable Insulated Isothermal RT‐PCR Assay for Identification of Influenza A (H7N9) Shows Good Performance in the Laboratory | September 2019 | Ken Inui, Tung Nguyen, Hsin‐Jou Tseng, ChuanFu Mark Tsai, Yun‐Long Tsai, Simon Chung, PawinPadungtod, ZHU Huachen, GUAN Yi,WantaneeKalpravidh, Filip Claes | National Key R&D Program 2017YFE0190800, USA Agency for International Development EPT-2, NIH HHSN272201400006C, Hong Kong Research Grants Committee Grant RGC-GRF 17118515, 17108417 , 17127714, Shenzhen Peacock Program Grant KQTD201203 National Key R&D Program 2017YFE0190800, USA Agency for International Development Grant EPT-2, NIH Grant HHSN272201400006C, Hong Kong Research Grants Committee Grant RGC-GRF 17118515, 17108417 , 17127714, Shenzhen Peacock Program Grant KQTD201203 | The Food and Agriculture Organization of the United Nations also contributed to this project | |
| 2016YFD0500302 | Safety and Immunogenicity of an 8 Year Interval Heterologousprime-boost Influenza AH7N7-H7N9 Vaccination | April, 2019 | Hana M. El Sahly, Robert L. Atmar, Shital M. Patel, Abbie Bellamy, Liwei Liu, Wenshan Hong, ZHU Huachen, GUAN Yi,, Wendy A. Keitel, the DMID 13-0033 Vaccine Study Group | NIH HHSN272201300015I, HHSN272200800002C, hhsn272201500002c, hhsn272201400006c, hongkong Research Grants Committee RGC-GRF 17127714 | Endy Buchanan, Suzanne Murray, Soju Chang, Valerie Riddle, Teresa Hauguel and Chris Roberts of the National Institutes of Health also contributed to this project. | |
| 2016YFD0500302 | Two Methods for Mapping and Visualizing Associated Data onPhylogenyUsingGgtree | October 2018 | YU Guangchuang, LIN Zanyu, ZHU Huachen, GUAN Yi* | National Key R&D Program of China 2017YFE0190800, National Institutes of Health HHSN272201400006C, Shenzhen Peacock Program KQTD201203 National Key R&D Program of China 2017YFE0190800, National Institutes of Health HHSN272201400006C, Shenzhen Peacock Program Grant KQTD201203 | Jianrong Yang, Sun Yat-sen University, Guanyang Zhang, University of Florida and Chenhao Li, Genome Institute of Singapore contributed to this article | |
| 2016YFD0500303 | Establishment and Preliminary Evaluation of a Method for the Detection of Chikungunya Virus Antigen | April 2017 | XING Xiaoyue, WU Wei, ZHANG Shuo, ZHANG Quanfu, LI Chuan, LIANG Mi Fang, LI Jiandong, LI Dexin* | – | – | |
| 2016YFD0500303 | Acquisition and Expression of Fab Segment Gene of Human-derived Anti-Zika Virus Monoclonal Antibody | December 2019 | YUAN Runyu, SUN Lina, SU Juan, JI Xunmin, LIANG Junhe, CHEN Maoyu, LIANG Mifang*, KE Changwen* | National Science and Technology Major Project of China 2018ZX09739002-004, Study on the Pathogenic Spectrum of Viral Infectious Diseases and the Variation Pattern of Viral Gene 2018ZX10713-002, Reform and Development Special Fund of the Ministry of Science and Technology of China 2016273, Guangdong Provincial Science and Technology Project Funding for the Prevention and Control of Zika Virus Disease 2016A020250001, Guangdong Medical Science Fund A2018187 | – | |
| 2016YFD0500303 | Single Dose of a rVSV-based Vaccine Elicits Complete Protection against Severe Fever with Thrombocytopenia Syndrome Virus | January 2019 | DONG Fangfang, LI Dandan, WEN Dan, LI Suhua, ZHAO Chaoyue, QI Yue, Rohit K. Jangra, WU Cuiping, XIA Dequan, ZHANG Xing, DENG Fei, Kartik Chandran, ZOU Zhen, YUAN Fei, ZHENG Aihua | Strategic Priority Research Program of the Chinese Academy of Sciences XDB11030800, State Key Laboratory of Integrated Pest Management Open Research Program IPM1511, IPM1603 | WIV led the study. Not all references cited in this paper are included; Qin Chuan, Bao Linlin, Gao Fu, Yan Yan also contributed to this study | |
| 2016YFD0500303 | Identification of Human Biting Midge in the Border Area of China, Laos and Vietnam in Jiangcheng County, Yunnan Province | October 2019 | BAI Fang, LI Zhao, YUAN Zhengju, WANG Juan, HE Yuwen, MENG Jinxin, LI Nan, XU Yong, WANG Jinglin* | National Natural Science Foundation of China 31460669, 31660714, Yunnan Science and Technology Department Key Fund Project, Yunnan Science and Technology Talents and Platform Plan 2018HB046 | – | |
| 2016YFD0500303 | Development and Application of a qRT-PCR Assay for the Detection of Akabane Virus | Mar 2019 | YUAN Zhengju, LIU Wei, LI Nan, MENG Jinxin, HE Yuwen, WANG Jinglin* | National Natural Science Foundation of China 31460669, 31660714, Natural Science Foundation of Inner Mongolia 2017MS03382, Yunnan Provincial Science and Technology Department Youth Fund 2014FD075 | – | |
| 2016YFD0500303 | Identification and COI Gene Sequence Analysis of the Non-biting Midge in Hohhot, Inner Mongolia, China | February 2019 | YUAN Zhengju, LIU Wei, LI Nan, MENG Jinxin, HE Yuwen, WANG Jinglin* | National Natural Science Foundation of China 31460669, 31660714, Natural Science Foundation of Inner Mongolia 2017MS03382, Yunnan Provincial Science and Technology Department Youth Fund 2014FD075 | – | |
| 2016YFD0500303 | Isolation and Molecular Identification of Gaeta Virus in Biting Midge | October 2017 | DONG Pei, LI Nan, HE Yuwen, XU Tiangang, YIN Jianzhong*, WANG Jinglin* | National Natural Science Foundation of China 31460669, Yunnan Provincial Science and Technology Department Youth Fund 2014FD075 | – | |
| 2016YFD0500303 | Morphology and Molecular Biology of Aedes aegypti mosquitoes in Tumertzuo and Alashanzuo Banners, Inner Mongolia | April 2019 | YUAN Zhengju, LIU Wei, HE Yuwen, MENG Jinxin, LI Nan, WANG Jinglin* | National Natural Science Foundation of China 31460669, 31660714, Natural Science Foundation of Inner Mongolia 2017MS03382, Yunnan Provincial Science and Technology Department Youth Fund 2014FD075 | – | |
| 2016YFD0500303 | Morphological and Molecular Biology Identification of Midge/CulicoidesSumatrae Collected in Jiangcheng County, Yunnan Province | October 2018 | LI Zhao, FU Qiang, BAI Fang, ZHANG Naxi, XU Yong, YUAN Zhengju, HE Yuwen,WANGJinglin* | National Natural Science Foundation of China 31460669, 31660714, Yunnan Provincial Science and Technology Department Youth Fund 2014FD075 | – | |
| 2016YFD0500303 | Genetic Characterization and Molecular Evolution of Urban Seoul Virus in Southern China | December 2019 | SU Qianqian, CHEN Yi, LI Meng, MA Jiajun, WANG Bo, LUO Jing, HE Hongxuan* | National Key R&D Program of China 2017YFD0501702, Strategic Priority Research Program of the Chinese Academy of Sciences XDA19050204, Chinese Academy of Sciences CZBZX-1, Beijing Innovation Consortium of Agriculture Research System BAIC04-2019 | Libiao ZHANG Quansheng LIU, Gaoming LIU also contributed to this project | |
| 2016YFD0500303 | Histone Acetyl Transferase TIP60 Inhibits Thereplication of Influenza A Virus by Activationthe TBK1-IRF3 Pathway | November 2018 | MA Guoyao, CHEN Lin, LUO Jing, WANG Bo, WANG Chengmin, LI Meng, HUANG Chengmei, DU Juan, MA Jiajun, Yungfu CHANG, HE Hongxuan* | External Cooperation Program of Chinese Academy of Sciences 152111KYSB20150023, Strategic Pioneering Science and Technology Special Project of the Chinese Academy of Sciences XDA19050204, Chinese Academy of Sciences CZBZX-1, Beijing Innovation Consortium of Agriculture Research System BAIC04 | – | |
| 2016YFD0500304 | A Single Residue in the αB Helix of the E Protein is Critical for Zika Virus Thermostability | January 2018 | XIE Dongyang, LIU Zhongyu, NIAN Qingkong, ZHU Ling, WANG Nan, DENG Yongqiang, ZHAO Hui, JI Xue, LI Xiaofeng, WANG Xiangxi, SHI Peiyong, QIN Chengfeng* | National Science and Technology Major Project of China 2017ZX09101005, 2017ZX10304402 National Natural Science Foundation of China 31770190, U170220023, 81661130162, 81661148054 | Institute of Biophysics, Chinese Academy of Sciences; Chengfeng Qin – Newton Senior Scholar, British Academy of Medical Sciences, NSF Outstanding Young Scientist 81522025, NSF Innovative Research Group 81621005 | |
| 2016YFD0500304 | American Strain of Zika Virus Causes More Severe Microcephaly than an Old Asian Strain in Neonatal Mice | October 2017 | ZHANG Feng, WANG Hongjiang, Qin WANG, LIU Zhongyu, YUAN Ling, HUANG Xingyao, LI Guanghui, YE Qing, Haozhen YANG, SHI Lei, DENG Yongqiang, QIN Chengfeng*, XU Zhiheng* | National Science and Technology Major Project of China 2017ZX09101005, 2017ZX10304402, National Natural Science Foundation of China 31430037, 31730108, Frontier Science Key Project of Chinese Academy of Sciences QYZDJ-SSWSMC007, Shanghai Brain-Wise Project 16JC1420500, Beijing Human Brain Project Z161100002616004 | Chengfeng Qin – Newton Senior Fellow, British Medical Association, Weixiang GUO and Xia JIN also contributed to this study | |
| 2016YFD0500304 | Biomimetic Inorganic Camouflage Circumvents Antibody-dependent Enhancement of Infection | October 2017 | Xiaoyu WANG, Yongqiang DENG, Dong YANG, Yun XIAO, Hui ZHAO, Qinggong NIAN, Xurong XU, Xiaofeng LI, Ruikang TANG*, Chengfeng QIN* | National Natural Science Foundation of China 81661148054, 81661130162, 21625105, 21571155 Natural Science Foundation of Zhejiang Province LY17B010001 Fundamental Research Funds for the Central Universities 2016QN81020 | Chengfeng Qin – Newton Senior Scholar, British Academy of Medical Sciences NAF003\1003, NSF Outstanding Young Scientist 81522025, NSF Innovative Research Group 81621005 | |
| 2016YFD0500304 | Characterization of the Contemporary Zika Virus in Immunocompetent Mice | August 2016 | ZHANG Nana, TIAN Min, DENG Yongqiang, HAO Jiaanan, WANG Hongjiang, HUANG Xingyao, LI Xiaofeng, WANG Yuguang, LING-Zhai ZHAO, ZHANG Fuchun& QIN Chengfeng* | State Key Laboratory of Pathogen and Biosafety SKLPBS1601, National Natural Science Foundation of China 81661130162, 31270974, 31470265 | Chengfeng Qin-Newton Senior Scholar NAF003\1003, NSF Outstanding Young Scientist 81522025, NSF Innovative Research Group 81621005, British Academy of Medical Sciences Chengfeng Qin – Newton Senior Scholar, British Academy of Medical Sciences NAF003\1003, NSF Distinguished Young Scientist 81522025 | |
| 2016YFD0500304 | Transfer of Convalescent Serum to Pregnant Mice Prevents Zika Virus Infection and Microcephaly in Offspring | December 2016 | WANG Shuo, HONG Shuai, DENG Yongqiang, YE Qing, Ling-Zhai ZHAO, ZHANG Fuchun, QIN Chengfeng*, Xu Zhiheng* | 973 Program 2014CB942801, 2013DFA31990, 2012YQ03026006, National Natural Science Foundation of China 31430037, 31271156, 81522025, 81621005 | – | |
| 2016YFD0500304 | Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate | September 2018 | CHEN Qi, WU Jin, YE Qing, MA Feng, Qian ZHU, Yan WU, SHAN Chao, Xuping XIE, Dapei LI, Xiaoyan ZHAN, LI Chunfeng, LI Xiaofeng, Xiaoling QIN, Tongyang ZHAO, WU Haitao, SHI Peiyong, MAN Jianghong, QIN Chengfeng | National Science and Technology Major Projectof China 2018ZX09711003, 2017ZX10304402, National Natural Science Foundation of China 31870912, 31770190, U170220023, 81661148054, 81572889, 31522029, 31670883, CAMS Innovation Fund for Medical Sciences 2016-12M-1-005, Beijing Science and Technology Commission Z161100000216154 | Chengfeng Qin – Newton Senior Scholar, British Academy of Medical Sciences, NSF Innovative Research Group 81621005, NSF Distinguished Youth 81661130162; Peiyong Shi – Awarded STARs from the University of Texas; CDC grant to the University of Texas Western Bay Area Center for Insect-borne Infectious Diseases, Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, UTMB CTSA J. Kleberg Jr. and Helen C. Kleberg Foundation Grant UL1TR-001439, NIH grant AI127744; Jeremy Rich, University of California, San Diego, also contributed to this study | |
| 2016YFD0500304 | Visualization of a neurotropic flavivirus infection in mouse reveals unique viscerotropism controlled by host type I interferon signaling | February, 2017 | LI Xiaofeng, LI Xiaodan, DENG Chenglin, DONG Haolong, Qiu-Yan ZHANG, YE Qing, YE Hanqing, HUANG Xingyao, DENG Yongqiang, ZHANG Bo, QIN Cheng-Feng* | National Key R&D Program of China 2016YFD0500400, National Natural Science Foundation of China 81572003, 31300151, 81621005, 31470265 | Chengfeng Qin – Newton Senior Scholar, British Academy of Medical Sciences NAF003\1003, NSF Innovative Research Group 81621005, NSF Outstanding Young Scientist 81661130162 | |
| 2016YFD0500304 | Study on the biological function of glycosylation of Zika virus envelope E protein | December 2018 | CHENG Mengli, HUANG Xingyao, DENG Yongqiang, LI Xiaofeng, QIN Chengfeng* | National Natural Science Foundation of China 81873964 | – | |
| 2016YFD0500304 | Advances in the structure and function of the Zika virus non-structural protein NS5 | September 2019 | HUANG Xingyao, YE Qing, LI Xiaofeng, QIN Chengfeng* | National Natural Science Foundation of China 81522025, 81621005, 8161148054, 31770190 | – | |
| 2016YFD0500304 | Progress in the study of the interaction between Zika virus and type I interferon response | January 2018 | JI Xue, ZHAO Hui, HUANG Xingyao, LI Xiaofeng, QIN Chengfeng* | National Natural Science Foundation of China 81522025, 81621005, 81661148054, 31770190 | – | |
| 2016YFD0500304 | A Peptide-based Viral Inactivator Inhibits Zika Virus Infection in Pregnant Mice and Fetuses | July 2017 | YU Yufeng, DENG Yongqiang, OUu Peng, WANG Xi, DAI Yanyan, YU Fei, DU Lanying, ZHANG Nana, TIAN Min, Jia-Nan HAO, Yu MENG, Yuan LI, Xiaohui ZHOU, CHEN Fuhe, Yuan Guoyong, QIN Chengfeng, JIANG Shibo& LU Lu | 863 Program 2015AA020930, National Key R&D Program of China 2016YFC1201000, 2016YFC1200405, 2016YFC1202901, National Natural Science Foundation of China 81630090, 81522025, 81661130162, 81672019 | The Food and Health Bureau, Hong Kong SAR, and the Department of Health, Hong Kong SAR, also contributed to this study by strengthening the Laboratory for Emerging Infectious Diseases. | |
| 2016YFD0500304 | Long Non‐coding Subgenomic Flavivirus RNAs have Extended 3D Structures and are Flexible in Solution | September 2019 | ZHANG Yupeng, ZHANG Yikan, LIU Zhongyu, CHENG Mengli, Junfeng MA, Yan WANG, QIN Chengfeng* & FANG Xiangyang* | National Key R&D Program of China 2016YFA0500700, National Science and Technology Major Project of China 2018ZX09711003, National Natural Science Foundation of China 81522025, 81621005, 31770190, sponsored by China Young Thousand Talents Program, Tsinghua University Independent Research Program, Beijing Advanced Innovation Center for Structural Biology | – | |
| 2016YFD0500304 | Near-atomic Structure of Japanese Encephalitis Virus Reveals Critical Determinants of Virulence and Stability | April 2017 | Xiangxi WNG, LI Shihua, ZHU Ling, NIAN Qinggong, Shuai YUAN, Qiang GAO, Zhongyu HU, YE Qing, LI Xiaofeng, XIE Dongyang, Neil Shaw, Junzhi WANG, Thomas S. Walter, Juha T. Huiskonen, Elizabeth E. Fry, QIN Chengfeng, David I. Stuart & RAO Zihe | 973 Program 2014CB542800, National Natural Science Foundation of China 31300151, 81330036, 31570717, 81520108019, 81621005, Strategic Priority Research Program of the Chinese Academy of Sciences XDB08020200, UK Medical Research Council G100099, MR / N00065X / 1, Wellcome Trust 090532/Z/07/Z | Chengfeng Qin – Newton Senior Scholar, British Academy of Medical Sciences, NSF Innovative Research Group 81621005, NSF Outstanding Young Scientist 81661130162; the Oxford Centre for Particle Imaging, UK, also contributed to this research, which was established with funding from the Wellcome Trust (060208/Z/00/Z) and supported by (093305/Z/ 10/Z) | |
| 2016YFD0500304 | Potent Neutralization of Hepatitis A Virus Reveals Areceptor Mimic Mechanism and the Receptorrecognition Site | January 2017 | WANG Xiangxi, ZHU Ling, DANG Minghao, HU Zhongyu, Qiang GAO, Shuai YUAN, Yao SUN, Bo ZHANG, Jingshan REN, Abhay Kotecha, Thomas S. Walter, Junzhi WANG, Elizabeth E. Fry, David I. Stuart, & RAO Zihe | 973 Program 2014CB542800, National Natural Science Foundation of China 81330036, 31570717, 81520108019, 81621005, Strategic Priority Research Program of the Chinese Academy of Sciences XDB08020200, Wellcome Trust 090532/Z/07/Z | Institute of Biophysics, Chinese Academy of Sciences, also contributed to this study; Oxford Centre for Particle Imaging, Oxford, UK, also contributed to this study, which was established with funding from the Wellcome Trust (060208/Z/00/Z) and supported by (093305/Z/10/Z) | |
| 2016YFD0500304 | Chloroquine, a FDA-Approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice | September 2017 | LI Chunfeng, ZHU Xingliang, JI Xue, Natalie DENG Yongqiang, TIAN Min,RoghiyhAliyari, Xiangyang ZUO, YUAN Ling, Shabbir Khan Afridi, LI Xiaofeng, Jae U. Jung, Karin Nielsen-Saines,QINXiaofeng⁎, QIN Chengfeng⁎, XU Zhiheng⁎, CHENG Genhong⁎ | 973 Program 2014CB942801, 2012YQ03026006, the National Science and Technology Major Project for Significant New Drugs Innovation and Development 2015ZX09102023, State Key Laboratory of Pathogen and Biosafety SKLPBS1601, National Natural Science Foundation of China 31670883, 1500145, 31430037, 91542201, 81590765, CAMS Innovation Fund for Medical Sciences 2016-12M-1-005, US National Institutes of Health R01 AI069120, AI056154, AI078389 502, Youth Funds for the Central Universities 332016125), Shanghai Brain-Intelligence Project 16JC1420500, Beijing Human Brain Project Z161100002616004 | Chengfeng Qin – Newton Senior Scholar, British Academy of Medical Sciences NAF003\1003, NSF Innovative Research Group 81621005, NSF Outstanding Young Scientist 81661130162 | |
| 2016YFD0500304 | A study on Host and Restriction Factors for Chikungunya Virus | May 2018 | YIN Han, ZHANG Leiliang* | – | – | |
| 2016YFD0500304 | Human-derived A/Guangdong/Th005/2017 (H7N9)Exhibits Extremely High Replication in the Lungs of Ferrets and is highly Pathogenic in Chickens | May 2019 | Shuran GONG, Feifei QI, Fengdi LI, Qi Lv, Guanpeng WANG, Shunyi WANG, Jing JIANG, Lin WANG, Linlin BAO*, QIN Chuan*. | National Science and Technology Major Project of China 2017ZX10304402-001, CAMS Innovation Fund for Medical Sciences 2016-12M-1-006, 2016-12M-1-014 | George Fu Gao, Yuhai Bi, Yanfeng Xu and Yanfeng Yao also contributed to this study | |
| 2016YFD0500304 | The battle against SARS and MERS Coronaviruses-Reservoirs and Animal Models | July 2018 | Shu-ran GONG, BAO Linlin* | National Science and Technology Major Project of China 2017ZX10304402-001-003, CAMS Innovation Fund for Medical Sciences 2016-12M-1-006, 2016-12M-1-014 | – | |
| 2016YFD0500305 | Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein | May 2019 | SONG Hao, Zhennan ZHAO, CHAI Yan, Xiyue JIN, LI Changyao, YUAN Fei, Sheng LIU, Zhengrong GAO, WANG Haiyuan, Jian SONG, Leonardo Vazquez, Yanfang ZHANG, TAN Shuguang, Carlos M Morel, YAN Jinghua, SHI Yi, QI Jianxun, GAO Feng*, George Fu Gao* | National Science and Technology Major Project of China 2018ZX10101004, 2015ZX09102024, 2018ZX09711003, 2018ZX10733403, National Natural Science Foundation of China 31872745, CAS Strategic Pioneering Science and Technology Special Project XDB29010000, CAS Youth Innovation Promotion Association 2017117, 2015078, the National Science Fund for Distinguished Young Scholars 81622031 Translated with www.DeepL.com/Translator (free version) | The Center for Bioimaging, Institute of Biophysics, Chinese Academy of Sciences, Beijing, also contributed to this study; Yuanyuan Chen, Bingxue Zhou and Zhenwei Yang, Institute of Biophysics, Chinese Academy of Sciences, also contributed to this study; F. Gao, as Principal Investigator of the Innovative Research Group 81621091 of the National Natural Science and Technology Foundation of China and the External F. Gao also contributed to this study as the Principal Investigator of the NSFC Innovative Research Group 81621091 and the External Collaboration Program 153211KYSB20160001 of the Chinese Academy of Sciences | |
| 2016YFD0500305 | Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus–derived CD8+ T Cell Epitopes and Host MHC | November 2016 | LIU Jun, LAN Jiaming, LIU Kefang, DENG Yao, YAO Yanfeng, Shaolian WU, CHEN Hong, BAO Linlin, Haifeng ZHANG, ZHAO Min, Qihui WANG, Lingxia HHAN, CHAI Yan, QI Jianxun, ZHAO Jincun, MENG Songdong, QIN Chuan, George Fu Gao, TAN Wenjie. | 973 Program 2015CB910500, National Science and Technology Major Project for the Control and Prevention of Major Infectious Diseases 2016ZX10004222-003, 2014ZX10004001-002, 2014ZX10004001-006, 2012ZX10004501-004, National Natural Science Foundation of China 81373141, 81401312, 81461168030, Guangzhou Medical and Health Care Joint Innovation Major Project 201604020011 | Jianfang Zhou, CDC, Stanley Perlman, University of Iowa, USA, L. Haagmans, Ron A.M. Fouchier, Erasmus MC, Rotterdam, The Netherlands, also contributed to this study; cross-research literature within the project, bringing together multiple teams | |
| 2016YFD0500305 | Structural and Functional Insights into MCR-2 Mediated Colistin Resistance | September 2018 | Xudong Wang, Qiong Lu, QI Jianxun, CHAI Yan, YouchunWang&GAO Fu | CAS Strategic Pioneering Science and Technology Special Project XDB08020100,External Cooperation Program of Chinese Academy of Sciences 153211KYSB20160001 | GAO Fu also contributed to this study as the chief researcher of the Innovative Research Group 81621091 of the National Natural Science Foundation of China | |
| 2016YFD0500305 | Structures of Human-infecting ThogotovirusFusogens Support a Common Ancestor with Insect Baculovirus | October 2017 | PENG Ruchao, Shuijun ZHANG, Yingzi CUI, SHI Yi, George Fu Gao, QI Jianxun | “973” Program 2013CB531502, 2014CB542503, National Science and Technology Major Project of China 2017ZX10303403, CAS Strategic Pioneering Science and Technology Special Project XDPB03, National Outstanding Youth Science Fund Project of National Natural Science Foundation of China 81622031, CAS Youth Innovation Promotion Association 2015078 | GAO Fu also contributed to this study as the chief researcher of the Innovative Research Group 81621091 of the National Natural Science Foundation of China | |
| 2016YFD0500305 | Structure of the Nsp2 PL2 Domain of the PRRSV Non-structural Protein and its Deubiquitinating Enzyme Function | June 2018 | ZHANG Lei, HONG Wenjiao, ZHANG Lilin, LAI Ruiqiao, SU Yanxin, ZHAO Chengxue, LU Dong, LIU Xianming, HUANG Jinhai*. | Tianjin Science and Technology Program Project 16YFZCNC00640, Tianjin Natural Science Foundation 17JCZDJC33900 | – | |
| 2016YFD0500306 | A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV | August 2018 | ZHAO Guangyu, Lei HE, SUN Shihui, QIU Hongjie, TAI Wanbo, Jiawei CHEN, Jiangfan LI, CHEN Yuehong, GUO Yan, Yufei WANG, Jian SHANG, Kaiyuan JI, Ruiwen FAN, DU Enqi, JIANG Shibo ,LI Fang , DU Lanying , ZHOU Yusen | National Natural Science Foundation of China 81571983, China Science and Technology Innovation Grant 3407049, SKLPBS1704, State Key Laboratory of Pathogen and Biosafety, NIH Grants R01AI137472, R21AI109094, R21AI128311, R01AI089728, r01ai110700, r01ai139092 | – | |
| 2016YFD0500306 | Bovine Adenovirus Type 3 Virions cannot be Rescued in Vivo after Full-length Viral Genome Transfection in the Absence of Detectable Polypeptide IX | July 2017 | Peng ZHANG, Qinghong XUE, Jing MA, Jingjing REN, Shuili XIA, Lu ZHANG, Wenbin WANG, Suresh K. Tikoo*, Enqi DU* | Natural Sciences and Engineering Research Council of Canada, Saskatchewan Health Research Foundation, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Grant No. SKLVBF201405, National Natural Science Foundation of China , Grant No. 31101803/C1803 | – | |
| 2016YFD0500306 | Comparison of Three Commonly Used Fusion Tags for the Expression of Nanobodies in the Cytoplasm of Escherichia Coli | January 2018 | Ze-hui LIU, Di HUANG, Xiangjing FU, Peng CHENG & DU Enqi*. | State Key Laboratory of Pathogen and Biosafety Open Research Project SKLPBS1522 | – | |
| 2016YFD0500306 | Melatonin Relieves Busulfan-Induced Spermatogonial Stem Cell Apoptosis of Mouse Testis by Inhibiting Endoplasmic Reticulum Stress | December 2017 | Yanhua CUI, Lipeng REN, Bo LI, Jia FANG, Yuanxin ZHAI, Xin HE, DU Enqi, Yiliang MIAO, Jinlian HUA, PENG Sha*. | National Key R&D Program 2016YFA0100203, National Natural Science Foundation of China 31572399, 31272518, Key Science and Technology Projects of Shanxi Province 2015NY157 | – | |
| 2016YFD0500306 | Surface Displaying of Swine IgG1 Fc Enhances Baculovirus-vectored Vaccine Efficacy by Facilitating Viral Complement Escape and Mammalian Cell Transduction | May 2017 | Zehui LIU, Yangkun LIU, Yuanyuan ZHANG, Yajuan YANG, Jingjing REN, Xiaoying ZHANG*, Enqi DU*. | State Key Laboratory of Pathogen and Biosafety Open Research Project SKLPBS1522, National Natural Science Foundation of China 31572556, Shaanxi Province Science and Technology International Cooperation Base Key Construction Program 2015SD0018 | – | |
| 2016YFD0500307 | Blockade of the C5a–C5aR Axis Alleviates Lung Damage in hDPP4-transgenic Mice Infected with MERS-CoV | April 2018 | Yuting JIANG, ZHAO Guangyu, Nianping SONG, LI Pei, CHEN Yuehong, GUO Yan, LI Junfeng, DU Lanying, JIANG Shibo, GUO Renfeng, SUN Shihui*, ZHOU Yusen*. | National Key R&D Program 2016YFC1202903, National Science and Technology Major Project for the Control and Prevention of Major Infectious Diseases 2017ZX10304402-003, National Natural Science Foundation of China 81571983, Military Logistics Research Project BWS14J058, 16CXZ039 | Directly involved in military research projects | |
| 2016YFD0500307 | Cryo-electron Microscopy Structures of the SARS-CoV Spike Glycoprotein Reveal a Prerequisite Conformational State for Receptor Binding | December 2016 | Miao DU, Wenfei Song, Haixia Zhou, Jingwei Xu, Silian Chen, Ye XIANG, Xinquan Wang | National Key R&D Program of China 2016YFA0501100, National Natural Science Foundation of China 81471929, U1405228, 31470721, 81550001 | – | |
| 2016YFD0500307 | Structural Definition of a Unique Neutralization Epitope on the Receptor-binding Domain of MERSCoV Spike Glycoprotein | July 2018 | GUI Miao, SONG Wenfei, ZHOU Haixia, XU Jingwei, CHEN Silian, XIANG Ye, WANG Xinquan*. ZHANG Senyan, ZHOU Panpan, WANG Pengfei, Yangyang LI, Liwei JIANG, Wenxu JIA, Han WANG, Angela FAN, Dongli WANG, SHI Xuanling, FANG Xiangyang, Michal Hammel, Shuying WANG, LI Xiaoyu, CEN Shan | National Key R&D Program of China 2016YFC1200902, National Natural Science Foundation of China 31470751, U1405228, 81530065, 81471929, Bill & Melinda Gates Foundation Grand Challenges Fund Program 81661128042 | Tan Wenjie, Chinese Center for Disease Control and Prevention, (CCDC), Yin Tianlei&JiangShibo, Hudan University, also contributed to this study; the Bill & Melinda Gates Foundation sponsored the study | |
| 2016YFD0500307 | Structural and Functional Definition of a Vulnerable Site on the Hemagglutinin of Highly Pathogenic Avian Influenza A Virus H5N1 | February 2019 | Pengfei WANG, Yanan ZUO, Jianfeng SUN, Teng ZUO, Senyan ZHANG, Shichun GUO, Xuanling SHI, Mifang LIANG, Paul ZHOU, ZHANG Linqi, WANG Xinquan | 973 Program 2014CB542500, National Science and Technology Major Project of China2018ZX10731101-002, 2017ZX1020110, National Natural Science Foundation of China 31470751, U1405228, 81530065, 8166112804 | – | |
| 2016YFD0500307 | An Integrative Genomic Analysis of Transcriptional Profiles Identifes Characteristic Genes and Patterns in HIV-infected Long-term Non-progressors and Elite Controllers | January 2019 | DING Jiwei, MA Ling, ZHAO Jianyuan, Yongxie LI, ZHOU Jinming, LI Xiaoyu*, CEN Shan*. | National Science and Technology Major Project for the Control and Prevention of Major Infectious Diseases 2018ZX10301408, National Natural Science Foundation of China 81772205, 18-I2M-3-004, CAMS Innovation Fund for Medical Sciences 2016-I2M-2-002 XYL and 2017-I2M-1-012 YXZ | – | |
| 2016YFD0500307 | Association of Gene Polymorphism of SDF1(CXCR12) with Susceptibility to HIV-1 Infection and AIDS Disease Progression-A Meta-analysis | February 2018 | DING Jiwei, ZHAO Jianyuan, ZHOU Jinming, LI Xiaoyu, YANbin WU, GO Mei*, CEN Shan*. | National Natural Science Foundation of China 81772205CS , 81361128017, CAMS Innovation Fund for Medical Sciences 2016-12M-2-002 | – | |
| 2016YFD0500307 | Host Long Noncoding RNA lncRNA-PAAN Regulates the Replication of Influenza A Virus | June 2018 | WANG Jing, WANG Yujia, ZHOU Rui, ZHAO Jianyuan, ZHANG Yongxin, YI Dongrong, LI Quanjie, ZHOU Jinming, GUO Fei, LIANG Chen, LI Xiaoyu, CEN Shan* | National Science and Technology Major Project for the Control and Prevention of Major Infectious Diseases 2018ZX10301408, National Natural Science Foundation of China 8150175, Beijing Key Laboratory of Infectious Diseases Project | The National Infrastructure for Microbial Resources NIMR-2014-3 provides reagents | |
| 2016YFD0500307 | Human MxB Inhibits the Replication of HCV | October 2018 | YI Dongrong, AN Ni, LIU Zhenlong, XU Fengwen, Kavita Raniga, LI Quanjie, ZHOU Rui, WANG Jing, ZHANG Yongxin, ZHOU Jinming, ZHANG Leiliang, AN JING, QIN Chengfeng, GUO Fei, LI Xiaoyu, LIANG Chen*, CEN Shan*. | National Science and Technology Major Project for the Control and Prevention of Major Infectious Diseases 2018ZX10301408, Canadian Institutes of Health Research HOP-143171 , Canadian Quebec Medical Research Fund International Exchange Program 31711520716 , National Natural Science Foundation of China 81772205, CAMS Innovation Fund for Medical Sciences 2016-I2M-2-002, 2017-I2M-1-012, Youth Fund of Peking Union Medical College Hospital 3332018096, Beijing Key Laboratory of Infectious Diseases Project | The National Infrastructure for Microbial Resources NIMR-2014-3 provides reagents | |
| 2016YFD0500307 | MOV10 sequesters the RNP of influenza A virus in the cytoplasm and is antagonized by viral NS1 protein | February 2019 | LI Jian, HU Siqi, XU Fengwen, ME Shan, Xiaoman LIU, YIN Lijuan, Fei ZHAO, Xiaoxiao ZHAO, Hong SUN, XIONG Zichen, ZHANG Di, CEN Shan, WANG Jianwei, LIANG Chen*, GUO Fei*. | National Natural Science Foundation of China 81601771, 81371808, 81528012, 81702451, 81401673, Canadian Institutes of Health Research CCI-132561, CAMS Innovation Fund for Medical Sciences 2018-12M-3-004, 2016-12M-1-014 | SHU Yuelong and WANG Dayan of the Chinese Center for Disease Control and Prevention also contributed to this study | |
| 2016YFD0500307 | Development of an anti-Zika virus drug screening model and its application | February 2019 | ZHOU Rui, SHI Xing, TIAN Dongfang, ZHANG Yongxin, YU Liyan, MA Xuemei, LI Xiaoyu, CEN Shan*. | CAMS Innovation Fund for Medical Sciences 2018-12M-3-004 | – | |
| 2016YFD0500307 | PKR-dependent cytosolic cGAS foci are necessary forintracellular DNA sensing | November 2019 | HU Siqi, Hong SUN, YIN Lijuan, LI Jian, MEI Shan, XU Fengwen, Chao WU, Xiaoman LIU, Fei ZHAO, ZHANG Di, HUANG Yu, REN Lili, CEN Shan, WANG Jianwei, LIANG Chen, GUO Fei*. | National Science and Technology Major Project of China 2018ZX10301408-003, 2018ZX10731101-001-018, National Natural Science Foundation of China 81601771, 81371808, 81528012, 81702451, CAMS Innovation Fund for Medical Sciences 2018-12M-3-004, 2016-12M-1-014, Canadian Institutes of Health Research CCI-132561, General Fund of Chinese Academy of Medical Sciences 2019-RC-HL-012, Fundamental Research Funds for Central Universities 333218202 | – | |
Annex III Index of Source File Information
This table records the location of all news, government materials and other public web information collected during the completion of the report. Important evidence/information is listed separately by its file name and its role is described for information purposes only.
| First level information | Second level information | Third level information | Fourth level information | File name | File type | Description |
| 1 Background Information | News from CCP-affiliated research institutions | Chinese Academy of Sciences | NA | 2011 Predecessor Project – “Molecular Mechanisms of Interspecies Infection and Disease Transmission of Important Viruses” Project Launched | Web Screenshot | The earliest research which indicates the CCP has studied the pathogens of human-animal diseases can be traced back to 2005 |
| Institute of Microbiology, Chinese Academy of Sciences as a Participating Unit Receives the 2017 National Science and Technology Progress Grand Prize | Web Screenshot | Joint research by several units on H7N9 and other viruses has made a major breakthrough | ||||
| Wuhan Institute of Virology held training on confidentiality–Wuhan Institute of Virology, Chinese Academy of Sciences | Web Screenshot | The work of Wuhan Institute of Virology involves confidentiality | ||||
| Wuhan Institute of Virology’s new viral research team was honored as an advanced group of “Women Building Success” by Chinese Academy of Sciences | Web Screenshot | The earliest research on bat virus at Wuhan Institute of Virology dates back to 2004 | ||||
| FondationMérieux | NA | The conference celebrating the 40th anniversary of reform and opening up. Who are the foreign friends on the podium? | Web Screenshot | France’s FondationMérieux is a key booster for the CCP in the Sino-French P4 Lab negotiations | ||
| Postdoctoral recruitment in the laboratory of Christopher Méliès at the Institute of Pathogen Biology | Web Screenshot | The French Mérieux Foundation’s laboratory assistance at a CCP’s university shows that the interests of the two parties are deeply intertwined | ||||
| NA | NA | [Keywords] biological resources, non-traditional security | Web Screenshot | How to define non-traditional security? Why is there an emphasis on the use of biological resources? | ||
| 2016-“Establishment Conference of Bacteriology Group of Medical Microbiology and Immunology Special Committee of Chinese Society of Microbiology” was held in Shanghai | Web Screenshot | Dan Hu of the Military Medical Research Institute of the Nanjing Military Region (known externally as the Eastern Theater Center for Disease Prevention and Control) is a member of it. | ||||
| Virology Committee of Chinese Society of Microbiology | Web Screenshot | Members of the CCP Virus Academic Consortium | ||||
| The 244th China Engineering Science and Technology Forum – “Joint prevention and control, strict prevention of exotic human-animal disease” was held in Beijing | Web Screenshot | The CCP People’s Liberation Army, under the name of the Academy of Engineering, its military-led research on human-animal infections was carried out at the same time as the 2016 virus project | ||||
| The 2nd International Forum on Influenza and Other Respiratory Viruses was successfully held at the First Hospital of Guangzhou Medical University | Web Screenshot | Malik was present at the event and the session focused on the topic. | ||||
| Official document issued by the CCP China | NA | NA | “AIDS and viral hepatitis and other major infectious diseases prevention and treatment” science and technology major special “Thirteenth Five-Year” general group list | Documentation | Members of the CCP Virus Academic Consortium | |
| The list of experts for the preparation of the 2018 declaration guide for the “Major Infectious Diseases such as AIDS and Viral Hepatitis” science and technology special projects | Documentation | Members of the CCP Virus Academic Consortium | ||||
| “AIDS and Viral Hepatitis and Other Major Infectious Disease Prevention and Control” science and technology major special projects in the year 2020 video defense evaluation experts list | Documentation | Members of the CCP Virus Academic Consortium | ||||
| The third national Human Infectious Pathogenic Microorganisms Laboratory Biosafety Review expert committee list | Documentation | Members of the CCP Virus Academic Consortium | ||||
| Compilation instructions of the national science and technology major special budget preparation system | Documentation | It is possible to decipher the meaning of the numbering of the various research programs of the CCP | ||||
| The official news release of the CCP | Health Care Commission (formerly Ministry of Health) | NA | NA | NA | (Same content, information output by different institutional ports, evidence retained) | |
| Ministry of Science and Technology National Major Project | NA | NA | NA | |||
| NA | NA | NA | [collation] 2016-2018 “13th Five-Year Plan” major special statistics | Documentation | The hand-organized collection of project names, lead units and prime movers of the key R&D programs of the CCP China from 2016 to 2018, partial listing of the implementation cycle and project funding | |
| NA | NA | NA | Introduction of Infectious Disease Control Special | Web Screenshot | The official introduction of the special infectious disease control | |
| NA | NA | NA | Introduction of National Science and Technology Major Special Projects | Web Screenshot | The official web page of the National Science and Technology Major Project explains |
| First level information | Second level information | Third level information | Fourth level information | File name | File type | Description |
| 2Virus Project Subject Information | NA | NA | NA | 2016 virus project introduction | Web Screenshot | A scientific report article from the Center for Disease Control and Prevention of the CCP China published in Acta Virology in January 2017, detailing the basic information and framework of the project |
| NA | NA | NA | [Finish] 2016 virus project details | Documentation | Basic information, participant information and funding information of the 2016 virus project of the CCP China, manually compiled | |
| 0Predecessor program content | NA | NA | 2005CB523000 – Study on the mechanism of interspecies infection and transmission of animal-derived viruses | Documentation | The tender for the 2005 virus project led by Gao Fu, complete with a description of its research objectives and course | |
| NA | NA | 2011CB504700 – Molecular mechanism of interspecies infection and transmission of important viruses causing disease | Documentation | The tender for the 2011 virus project led by Gao Fu, complete with its research objectives and route | ||
| 2016 Virus Project Literature | 2016YFD0500300 | Several | (Several, literature on the2016 Virus Project – all) | Documentation | Research results that were involved in the 2016 virus project and published before January 1, 2020 were collected as much as possible based on project information. Corresponding authors’ affiliations were classified in the literature. | |
| 2016YFD0500301 | (Several, literature for topic 1 of the 2016 Virus Project) | |||||
| 2016YFD0500302 | (Several, literature for topic 2 of the 2016 Virus Project) | |||||
| 2016YFD0500303 | (Several, literature for topic 3 of the 2016 Virus Project) | |||||
| 2016YFD0500304 | (Several, literature for topic 4 of the 2016 Virus Project) | |||||
| 2016YFD0500305 | (Several, literature for topic 5 of the 2016 Virus Project) | |||||
| 2016YFD0500306 | (Several, literature for topic 6 of the 2016 Virus Project) | |||||
| 2016YFD0500307 | (Several, literature for topic 7 of the 2016 Virus Project) | |||||
| Research results of the dead CCP scientists | Key deceased scientists | Zhao Zhendong | (Several, various papers published by Zhao Zhendong) | Documentation | Zhao Zhendong, a researcher at the Institute of Pathogenic Biology, Chinese Academy of Medical Sciences, died mysteriously of heart disease in 2020 and can be shown to be a key participant in the 2016 virus project | |
| Zhao Yongfang | (Several, various papers published by Y.F. Zhao) | Documentation | Zhao Yongfang, a researcher at the Institute of Biophysics of the Chinese Academy of Sciences, died mysteriously in 2016 in a PLA hospital. His unit during his lifetime was a key national research unit in proteinology with outstanding results, and it is believed that the Institute was even created specifically for this person | |||
| Additional Important information | Wuhan Institute of Virology | NA | Important progress in Middle East respiratory syndrome coronavirus research | Web Screenshot | Two fixed-point mutations can infect people across species | |
| NA | The CCP’s infectious disease prevention and control system fails | Web Screenshot | Few domestic P3 laboratories were able to conduct experimental analyses after the COVID-19 outbreak, suggesting that officials are controlling direct contact between the research side and the virus | |||
| NA | CCP researchers are very clear about the ADE effect | Web Screenshot | It was clear in an interview with Zhou Peng of Wuhan Institute of Virology in 2018 that the ADE effect of the virus is more frightening than the virus itelf | |||
| NA | Wuhan P4 laboratory officially opened | Web Screenshot | SARS outbreak at the end of 2002, the establishment of a P4 lab was proposed to 2003; the Chinese Academy of Sciences Biosecurity Large Science Center is suspected to be a cover nominal unit for conducting military research | |||
| NA | Wuhan Institute of Virology and Wuhan Customs cooperated in the 2019 Military Games | Web Screenshot | In 2019, Wuhan Institute of Virology collaborated with Wuhan Customs before the outbreak (followed by a coronavirus exercise on “pneumonia of unknown origin”) | |||
| Shantou University | NA | Shantou University 2016 Project Topics | Documentation | Side testimony Guan Yi participated in the 2016 virus project at Shantou University | ||
| NA | Shantou University Li Long’s blog post: To the lost years and graduate career | Web Screenshot | The diary of a fellow graduate student, allegedly supervised by Guan Yi, records the work of the Shantou University Virus Research Institute | |||
| NA | Guan Yi’s team at Shantou University: “Running with viruses, only gold medals and no silver medals” | Web Screenshot | The relationship between Guan Yi and the CoV research topic is further explained: Guan Yi’s team is focused on the infection mechanism; there is collaboration with the Shanghai Pasteur Institute; and the MERS virus samples from the Middle East in the hands of the CCP were obtained by Guan Yi. | |||
| NA | Shantou team wins National Science and Technology Progress Grand Prize for the prevention and control of human H7N9 infection | Web Screenshot | Guan Yi is also involved in the research project of Shu Yuelong, whose team is focusing on the mechanism of infection | |||
| Reported by the CDC Virus Diseases Institute | NA | 160203 The discovery of Human Novel H7N9 Avian Influenza Virus and Its Pathogenetic Study won the 1st prize of the 2015 China Medical Science and Technology Award | Web Screenshot | Before 2015, Shu Yuelong had conducted research on avian influenza in collaboration with the University of Hong Kong, and yielded some results | ||
| NA | 161130 Strengthening Research on Cross-species Infection and Transmission Mechanisms to Enhance Prevention and Control of Major Infectious Diseases | Web Screenshot | Project kick-off meeting of the 2016 Virus Program. Xia Xianzhu participated; the photos are basically of the project’s various subject leaders; Gao Fu gave an update on the progress of the study, consistent with the analysis of the 2005-2015 virus research predecessor project | |||
| NA | 161216 National Key Research and Development Program “Research on the Occurrence and Dispersal Mechanism of Important Emerging and Emerging Pathogens” Project kick-off meeting held in Beijing | Web Screenshot | Other viral research projects headed by Shu Yuelong in 2016, suspected to be involved in functional protein modification | |||
| NA | 170425 Strengthen the Joint Prevention and Control Mechanism, and Jointly Deal with Exotic Human-Animal Diseases | Web Screenshot | The 2016 virus project related meeting attended by the PLA Academy of Military Sciences | |||
| NA | 170727 The first “Hands-on Training Course on Unexplained Pneumonia Surveillance and Human Coronavirus Detection Techniques” was successfully held | Web Screenshot | Targeted infectious disease detection training in 2017, which also included the detection of avian influenza variants | |||
| NA | 170913 China CDC International Cooperation Department “came to our institute to conduct foreign-related national security education activities” | Web Screenshot | Indicates that the CDC has research projects that involve confidentiality | |||
| NA | 171120 The annual promotion meeting of the National Key Research and Development Program “Study on the Cross-Species Infection and Transmission Mechanism of Major Sudden Zoonotic Diseases” and the evaluation meeting of “2017 Vector Biology Development Strategy Research” was successfully held | Web Screenshot | There were 22 people in charge of the 7 subjects | |||
| NA | 181030 National Key Research and Development Program “Research on Cross-Species Infection and Transmission Mechanism of Major Outbreak of Human-Animal Infectious Diseases” was successfully held in the mid-term inspection meeting | Web Screenshot | The mid-term inspection of the 2016 virus project was held at Shantou University, indicating the importance of Shantou University | |||
| NA | 181114 Institute of Viral Diseases successfully held the 2018 National “Hands-on Training Course on Surveillance of Pneumonia of Unknown Cause and Human Coronavirus Detection Techniques”. | Web Screenshot | Targeted infectious disease detection training in 2018, which also covers detection of avian influenza variants | |||
| NA | 190920 National Key Research and Development Program “Research on Cross-species Infection and Transmission Mechanism of Major Emerging Human-Veterinary Diseases of Animal Origin” 2018-2019 Project Promotion Meeting was successfully held | Web Screenshot | This indicates that the 2016 virus project is winding down and the research is focused on the molecular mechanism of the subject | |||
| NA | 191024 Emergency Technology Center of the Institute of Viral Diseases successfully held the 2019 National Training Course on Research Advances and Detection Techniques for Common and Emerging Respiratory Virus Infections | Web Screenshot | The 2019 training on targeted infectious disease detection also includes the detection of avian influenza variant virus and smallpox monkeypox orthopox virus | |||
| Gates Foundation | NA | 2016 NSFC and Bill & Melinda Gates Foundation (BMGF) Grand Challenge Collaborative Research Program Approval Notice | Web Screenshot | Based on the fact that Lu Lu and Linqi Zhang are also participants in the 2016 Virus Project, it indicates that the Gates Foundation may also be involved in the 2016 Virus Project | ||
| NA | NA | In 2013, the CCP launched the “Search for Virus” program | Web Screenshot | Wuhan Institute of Virology began to acquire viruses from all parts of China in 2013 | ||
| NA | NA | Harbin Veterinary Research Institute Large Animal P4 Laboratory | Web Screenshot | According to AAF’s product case presentation, its partner, the Harbin Veterinary Research Institute of the Chinese Academy of Agricultural Sciences, has established a large animal biosafety level 4 laboratory | ||
| 3The Virus Project’s relationship with the University of Hong Kong | 1Project Funding Record of Malik Peiris / University of Hong Kong | NA | NA | National Natural Science Foundation of China and Research Grants Council Joint Research Grants Fund 2018-19 List of Funded Research Projects | Web Screenshot | It indicates that Malik of the University of Hong Kong and Jinli Zhao of Guangzhou Medical University collaborated on CoVresearch |
| 2Important Media Coverage | NA | NA | Malik received an invitation to the Wuhan Institute of Virology event | Web Screenshot | It explains Wuhan Institute of Virology’s intention to cooperate and exchange with Malik | |
| NA | NA | HKU collaborates with the National Respiratory Laboratory under Guangzhou Medical University | Web Screenshot | It shows that Guangzhou Medical University is one of the channels to establish cooperation between mainland and Hong Kong universities | ||
| NA | NA | Goldcorp Medical’s relationship with Guangzhou Medical University and Zhong Nanshan | Web Screenshot | Goldfield Medical is essentially a school-run enterprise of Guangzhou Medical University, and the founder of the enterprise has close personal ties with Zhong Nanshan | ||
| NA | NA | Goldcorp Medical hires Malik as a consultant | Web Screenshot | Malik | ||
| NA | NA | The capital behind Goldcorp Medical | Web Screenshot | The CCP’s Jiang family background behind Goldcorp | ||
| 3Supported by the CCP & Hong Kong Common Fund | NA | NA | (Several) | Documentation | The establishment of joint research between Hong Kong and China from the International Cooperation Division of the National Natural Science Foundation of China | |
| 4Other Information | Virus Research National Science and Technology Report Summary | NA | NA | (Several) | Web Screenshot | From the International Science and Technology Reports Search page of the Ministry of Science and Technology of the CCP China, a total of 73 abstracts of virus-related research reports were collected |
| National Natural Science Foundation Records | Several | several | (Several) | Web Screenshot | From the results of the project query of the National Natural Science Foundation of China, Collect the fund application status of the relevant figures of the virus plan from 2004 to 2019 | |
| Information on other virus research | Zika virus | NA | (Several) | Web Screenshot / Documentation | Zika virus-related research led by Qin Chengfeng at the Institute of Microbial Epidemiology, Chinese People’s Liberation Army Academy of Military Medical Sciences | |
| Wuhan Institute of Virology research | Annual Report | (Several) | Documentation | Annual reports of laboratory operations for previous years from the Wuhan State Key Laboratory of Virology. The query revealed that two researches of the laboratory were confidential in 2016 | ||
| Avian influenza virus | NA | (Several) | Documentation | Research results related to avian influenza published by domestic research institutions of the CCP |
Translation: 謐雪兒郭, 许先生, Ranting, 夏星湖
Proofread: DT团队, 文永
Cover photo: 诺亚方舟
Other articles in this series:
Deciphering CCP’s Virus Research Programs – Preamble
Deciphering CCP’s Virus Research Programs – Part 1: the 973 Program
Deciphering CCP’s Virus Research Programs – Part 3: the Five-Year Plan
Deciphering CCP’s Virus Research Programs – Part 4: the 2016 Virus Program
Deciphering CCP’s Virus Research Programs – Part 5: Details of the 2016 Virus Program
Deciphering CCP’s Virus Research Programs – Part 6: the Hong Kong Connection
Deciphering CCP’s Virus Research Programs – Part 7: Other Related Projects