DT EXPOSÉ OF CHINESE P4 BIOSAFETY LABORATORY – SEASON 2 (6)

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【DT EXPOSÉ】

Preamble

In the preceding essay, we have known through information and data that in China there are two P4 laboratories – one is Wuhan Institute of Virology, the other Harbin Institute of Virology. We also have known that there are two P3 laboratories in Wuhan – one in Wuhan University, the other in Wuhan Institute of Virology; these two P3 labs use the same title the National Key Laboratory of Virology. So, what is the job of these two P3 labs? What is the relationship between P3 labs? What are the relationships among P3 labs and P4 labs? What is the strategic deployment among them? We will figure out in the following essay.

Here is the detail.

The following is a memorial article with full emotion and sincere.

In memory of the famous virologist Academician Tian Bo – his research achievements for public good and scientific spirit enlightening successors

Author: Professor Guo Deyin China Virology English Version Dec. 17, 2019

China Virology English Version I F:2.467

Official Account ID of Wechat: virologica

Guo Deyin, Dean of School of Medicine, Sun Yat-sen University

Tian Bo, the famous virologist Academician of out country, was born in Huantai County in 1931, and unfortunately passed away in Beijing in Dec. 15, 2019. His immortal demise is a huge loss to our scientific community, especially the virology community. As his student and colleague, we have lost an insightful leader, a good mentor with magnanimity, and a respectable senior. Mr. Tian was the honorary editor of Virologica Sinica. Therefore, I borrow a little room of your journal to briefly review Academician Tian Bo’s research achievements and academic contributions in the field of virology, remembering his rigorous, pragmatic and innovative spirit, and recalling his gentleness and elegance as a master of the leader and also an elder.

My interest and research work in virology began with a master’s thesis in Academician Tian’s laboratory. After graduation, I was recommended by Academician Tian to go to Germany for a doctorate. After that, I worked at the University of Helsinki, Finland for seven years. And then I was recalled by Academician Tian to work for the country, and at the same time I directed my research from plant virus to medical virus. In 2002, as an assistant and colleague, I assisted him in establishing a modern virology research center in Wuhan University, and preparing to build the Ministry of Education and the National Key Laboratory of Virology. I followed Academician Tian for more than 30 years, and I have gained a lot of influence from his teachings and academics, and therefore have a lot of understanding of his academic thoughts and academic achievements. However, because of the fact that I am very ignorant, I can only carry out a simple review and summary, and may fail to be consummate.

1. Pursuing academic innovation and solving practical problems

The youth of Academician Tian Bo was during the War of Resistance Against Japan and the War of Liberation. He witnessed the huge disaster that the Japanese invasion of China brought the poor and weak to China at that time. And he determined to study hard in order to contrast his country one day. After graduating from university in 1954, he was assigned to the Institute of Microbiology of the Chinese Academy of Sciences, and began to study plant viruses. One of the major problems facing the country at that time was how to increase crop yields and solve the problem of food and clothing for the people. Therefore, he hoped to contribute to national food production through the study of plant virology. The first scientific question he chose to study was the degradation mechanism of crop varieties and research and development of related virus prevention and control technologies. The research in this field spanned from the 1950s to the 1980s.

At this stage, his main academic contributions are: a) Clarification of the function and mechanism of viruses and temperature in the degradation of potato varieties, and development of potato detoxification (i.e. virus removal) and stock maintenance techniques through stem and tip tissue cultivation. It has been widely used in potato production, resulting in huge social and economic benefits, and the detoxification technology was later applied to other asexual reproduction plants. b) Attenuated N-14 attenuated strain (similar to mammalian attenuated vaccine) was obtained through mutation and screen of Tobacco mosaic virus (TMV) by chemical mutagen. Once vaccine the strain plants will obtain anti-viral ability against infection by virulent strains. TMV can infect more than 300 kinds of plants, and the use of the attenuated strain has prevented huge economic losses of various crops in China. c) the first one in the world to propose the idea of using viral satellite RNA to control viruses, and develop a satellite RNA biocontrol agent for cucumber mosaic virus (CMV, which can also infect hundreds of plants), opening up a new way of plant virus control. d) As one of the earliest pioneers in the field of plant genetic engineering in China, he took the lead in applying gene recombination technology and ribozyme-based viral RNA degradation technology to plant virus control, and developed new tobacco and tomato strains with high disease resistance. In the 1950s and 1960s, scientific research conditions of our country were still relatively primitive, making it difficult to conduct systematic biochemical and molecular biology research. However, Mr. Tian was able to base on realistic conditions, face the major national needs, grasp the important scientific and technological issues of the time, carry out long-term and in-depth exploratory research, and thus achieved fruitful results. His scientific feelings of serving the country and the scientific spirit of pragmatic research are always worth remembering.

Academician Tian Bo working in the laboratory

2. Valiantly standing on the academic frontier and producing first-class results

During his academic career, Mr. Tian has undergone a tremendous transformation from traditional virology to modern virology, from plant virology to medical virology, and at every stage he was able to stand at the forefront of academics, open up new research fields, and promote the development of virology in China. The detoxification technology of stem-tip cultivation and the screening of attenuated strains and virus control technology he established in the 1950s and 1960s were the cutting-edge technologies in this field at that time. The more importantly, the use of satellite RNA preparations to prevent and control viruses proposed by him was a conceptual innovation in the field of international virology. Since the early 1970s, Mr. Tian has focused great attention on the discovery and research of new pathogens and subviral agents with a keen eye and profound scientific thinking. He was the founder of viroid research in China. The new viruses he discovered, such as the burdock dwarf virus, were included in the classic book “The Viroids” by T.O. Diener, and he used the ribozyme function that the virus carries to develop antiviral plants. He was the first to start research on satellite RNA and satellite RNA viruses in China, and prepare them into antiviral ingredients. He was the pioneer of prion research in China, and the first to propose the Chinese translation of prion.

By the early 1990s, China had solved the basic food and clothing problems, and Mr. Tian began to pay attention to the huge problems in the field of medical virology in China, such as the widespread prevalence of hepatitis B, the threats posed by HIV and the existential risks of new emerging viruses. He courageously made major adjustments in the field of research in his sixtieth year, gradually shifted from plant viruses to medical virus research, and continuously achieved innovative academic achievements. For example, for the first time, he isolated a virus-specific peptide that binds to heat shock protein gp96 from liver cancer tissues of patients infected with hepatitis B virus, and discovered the mechanism by which heat shock protein participates in virus antigen processing, providing a theoretical basis for the development of anti-hepatitis B virus drugs; a variety of inhibitors against HIV was developed in his laboratory; after the SARS outbreak, his research team quickly developed a viral membrane fusion inhibitor that effectively inhibited the infection of SARS virus, providing the basic condition for the prevention and control of SARS and social stability under the circumstances at that time. His courage and innovative spirit of daring to constantly challenge the frontiers of science is always worth learning for future generations.

Academician Tian Bo gave an academic presentation during SARS

3. Forward-look strategic planning and leading the development of discipline

Academician Tian Bo has participated many times in the formulation of development plan of China’s science and technology and Chinese Academy of Sciences, and has put forward a series of consulting suggestions, which have brought a positive impact on China’s science and technology development. In the field of international virology, he has led the development of multiple virology fields, such as the research of viral satellite RNA as mentioned previously. With regard to the development of virology in China, he has a long-term vision, and has conducted a number of forward-looking plans for research in new areas of virology. For example, the Key Laboratory of Pathogenic Microbiology and Immunization of Chinese Academy of Sciences proposed by him has become an internationally important laboratory for virus structure and virus immunity, improving the international status of China’s virology community significantly. In 2001, at a very old age, he was employed as a special professor of Wuhan University, leading the establishment of Wuhan University Modern Virology Research Center. He proposed a number of important measures to the school at the time, playing a major role in promoting the development of the virus discipline at Wuhan University and having a long-term and profound impact. He proposed that, according to the development trend of the virus discipline and tremendous demands of our country, the research of virus discipline of Wuhan University should shift from the traditional plant virus and insect virus to medical viruses, that because of the continuous emergence of major emerging viruses and their harmful impact on human being, Harm, Wuhan University should establish a third-class biosafety laboratory, or P3 laboratory, and build a modern virology research center based on this, and that the virology discipline of Wuhan University should have an international perspective and ambitious goals, and should focus on modern virology research to effectively and efficiently gather first-class talents and carry out original research on important scientific issues related to human major viral diseases. Under his leadership, Wuhan University established the first P3 laboratory in Chinese universities. Although the laboratory encountered outbreak of SARS virus soon after its establishment, we had some research results quickly. Later, Wuhan University established an animal P3 laboratory and became the first high-level biosafety laboratory in China that obtained CNAS certification. These forward-looking measures have greatly promoted the development of the virology discipline of Wuhan University, and soon after SARS, the Key Laboratory of Virology were established. His grand vision of the development of virology, his deep thinking and forward-looking deployment of virology issues are always worthy of continuous understanding by my generation.

Discussing work in the lab with Academician Tian Bo

4. Indifference to fame and fortune in life and devotion to academic research

Academician Tian Bo has worked hard for 65 years in the field of virology and has never left the front line of scientific research. In the 1970s and 1980s, Academician Gao Shangyin and the leaders of the Chinese Academy of Sciences repeatedly tried to persuade him to serve as the director of the Wuhan Institute of Virology, Chinese Academy of Sciences, but he refused. He politely said that he was only suitable for research, not for executive leadership. After working with Wuhan University for more than ten years, I deeply feel that Mr. Tian’s work at Wuhan University is purely out of affection for Wuhan University and love for virology, and is committed to promoting the development of modern virology in China irrespective of any personal interest. He has always regarded his work at Wuhan University as a very meaningful thing in his life. In the early days of the establishment of the Modern Virology Research Center, a biotechnology company in Wuhan, out of respect for Academician Tian and support for its research work, funded 2 million yuan for related research, but Mr. Tian used all of the funding to support research works of several young scholars. As a horizontal cooperation fund, all the personal deductions prescribed by the school was used for subsidies and rewards for graduate students and young teachers. Additionally, he always refused bonuses issued by research centers and colleges. In terms of the use of scientific research funds, his requirements are extremely strict, and every effort is made to save money. He often said that every cent of the funds is earned by the working people in toils, bloods, and sweats, and we must make careful calculations. The school approved 16 million yuan for the construction of a modern virology research center, but with the efforts of Mr. Tian, the construction of the center only used 12 million yuan. As an old man, he often travels between Beijing and Wuhan in economy class. During the research work of the SARS virus, he often ate simple lunches with our young people in order to devote more time to scientific research. When establishing the SARS research topic in the school, he, like a young teacher, prepared the PPT report seriously, and personally made the report statement and argument, showing the rigorous scientific attitude and serious work spirit of an old scientist and inspiring everyone present. His indifference to fame and fortune and scholarly style of devoted research set an example for young scholars.

SARS research offensive period

5. Cultivating students and demonstrating the style of a master

Academician Tian Bo has been trying his best to cultivate, help and support the development of young scholars, and vigorously introduce all kinds of excellent talents. For example, in order to promote the development of the virology field of the Institute of Microbiology, the Chinese Academy of Sciences, he promoted the introduction of Dr. Gao Fu from the United Kingdom, and gave all his possible support. Professor Gao Fu is currently an academician of the Chinese Academy of Sciences and an international top virology expert. At Wuhan University, he introduced and supported many young scholars through the construction of the Modern Virology Center and the Key Laboratory of Virology. In addition to the fact that Professor Wu Jianguo and I returned to Wuhan University from abroad as his former students, he also provided development conditions for young talents such as Zhang Linqi and Professor Chen Zhiwei, laying a solid foundation for their return to China for future development. At present, Professor Zhang Linqi and Professor Chen Zhiwei are both well-known experts in the field of HIV. They are respectively the director of the Comprehensive HIV Research Center of Tsinghua University and the director of the AIDS Research Institute of the University of Hong Kong. Later, Mr. Tian actively introduced Professor Jiang Shibo, an internationally renowned expert in the field of antiviral peptide drugs, and provided strong support for his domestic research. At present, Professor Jiang Shibo is a national expert and director of the Institute of Pathogenic Biology of Fudan University. In 2005, Wuhan University introduced Professor Shu Hongbing, an expert in cell biology, as the dean of the School of Life Sciences. Mr. Tian fully supported his research work, and even converted part of the office into a laboratory for his use and offered three graduate students to participate in his research. At the same time, all conditions of the Modern Virology Research Center are required to be open to Professor Shu’s research group. These measures played an important role in the timely start of the newly arrived dean’s research work. Professor Shu Hongbing is currently an academician of the Chinese Academy of Sciences and an internationally renowned natural immunity expert. Mr. Tian was also very concerned about young students. He always had answers to his students once they had questions. And he personally guided the subjects of each graduate student till he was hospitalized. He still asks the graduate student about the progress of the subject and is concerned about the development of young scholars. His style and spirit of master who loves talents and is willing to be ladder for others are always worth remembering.

(Note: Academician Tian Bo is also the doctoral supervisor of Wang Yanyi)

The above are just some of the deeper thoughts that the author has in getting along with Mr. Tian. This article, which was written in a hurry, is not enough to fully reflect Academician Tian’s academic achievements and master style. On the occasion of the 80th birthday of Academician Tian Bo in 2011, Science Press published Anthology of Tian Bo’s Virology, which systematically introduced Academician Tian Bo’s academic career and scientific research achievements. At the same time, Gao Fu and I compiled Virologist: Academician Tian Bo, which described his touching stories of being a man, a teacher and a scholar from different sides by Mr. Tian’s students, colleagues and unit leaders.

Academician Tian Bo rests forever, and his spirit lives forever!

Written in Guangzhou on Dec.16, 2019

The emotional article was written by Guo Deyin in memory of his tutor. I believe most of the information is fact. The article published by Guo Deyin reveals a lot of information that we don’t know in the past:

  1. The relationship between Tian Bo and several key people
  2. The key function and important status that Tian Bo played in it
  3. More importantly, the article is of an implicit expose that reveals the real plan and organizer of the layout of genetic weapons.
  4. Other information

I will use a table to sort out the relationship:

The following is the explanation of this article. Please prepare your beating heart well.

1. Take a look at the time and place that the article published

Author: Professor Guo Deyin China Virology English Version Dec. 17, 2019

China Virology English Version I F:2.467

Official Account ID of Wechat: virologica

That’s to say, it was published in Dec. 17, 2019. The article was completed in Dec. 16, 2019, which is less then two days after Mr. Tian Bo’s demise in Beijing on the afternoon of Dec. 15, 2019. That is too fast according to the editing speed of a magazine. But an important fact is that Guo Deyin is a favorite student of Tian Bo. He has been following the teacher for more than 30 years. Normally, he should help Tian’s families to prepare for the aftermath, rather than write a recollected article. so, there is only one possibility – this article was already been finished and was chose an appropriate time to publish in the appropriate media. Let’s take a look at December 17, 2019. What else happened besides the demise of Mr. Tian Bo?

one case of an asymptomatic infected person was reported in Qunhai, Hainan
The chairman of Changjiang Property and Casualty Insurance Co., Ltd., who is at the helm of the company for 6 years, died of new coronavirus
Who sounded the alarm of prevention and control of Wuhan pandemic?

That’s to say, the Wuhan epidemic has already occurred on December 17, 2019 or earlier. The medical treatment of exact infected person was on December 27, which is 10 days later. The afterwards experience of infected people shows that many people have already been infected on December 17, 2019. So, the publication date of the article by Guo Deyin, the beginning of Wuhan epidemic, and the date of demise of Mr. Tian Bo are almost simultaneous.

Let’s find out when did Miles Guo unravel Guo Deyin. It was Feb. 4, 2020, which was after the outbreak of Wuhan pandemic in China.

This is a war, Miles Guo said, PLA acknowledged that the virus was man-made.

I believe that the article written by Guo Deyin that was full of memory is carefully designed for each sentence. So, what is this article for? This article is not published in the public but only published in professional journals. But it is aimed at professional or specialized people. I think it is a kind of shouting, or conveying a important message, that is to tell everyone who is in the article that Mr. Tian Bo has passed away, and in the following pandemic, all shut up.

So, what is the significance of the demise of Tian Bo at this juncture point? Why is there always the demise of scientists at important time? The last one is Zhao Yongfang, now Tian Bo. DT the Digger is never the creator of conspiracy theory, but the truth dug out is always brutal.

So, DT regards this article written by Guo Deyin as a nuke-level expose, because the article exposes the true organization.

OK. Take a look at the first story of two stories before we continue digging the article.

First story: the story of two laboratories

The first story is about “the two Wuhan labs under the same mask” In the previous dig essay, we have unveiled some key information, and proved P3 laboratory safety management framework: the relationship among the competent unit, laboratory managers, academic committees, and trusteeship units. Let’s interpret the academic committee and management committee of these two laboratories. Now the academic committee.

Let me first explain that this form would not be so important without Guo Deyin’s article. If we, according to Guo Deyin’s account, learned Tian Bo ’s importance to these two laboratories in Wuhan, then we can understand that this form is extremely important and reveals many secrets of the development of the new coronavirus. Of course, a lot of information needs to be dug by DT through this form to prove it. However, the fact is that before Miles Guo unraveled his real name (including his role in this plague or biochemical war), he had eagerly released the prepared commemorative article for shouting. But the article, along with the list published on the Wuhan university’s website, inadvertently reveals a big secret, which is the reason how did this viral weapon come into being and when did it happen? To whom is the weapon finally handed over? Of course, the secrets revealed by Guo Deyin’s article are not only these, we will continue to reveal them.

Well, go straight to the topic, what does the above form imply? The core is the change and the time of the change.

Let’s recall the disclosure of the safety management system of the National Key Laboratory of the Chinese Communist Party in the previous article. The focus is not on whether leakage can occur, but on the CCP’s absolute safety control of the National Key Laboratory. That means that the gun must be secure and kept firmly in hands. There should be no accidents. If you understand this point, you will know the meaning and profound connotation of this structure, so the truth hidden in this form can be seen clearly.

Briefly speaking, the reason why the academic committee is important is that it manages the money. Who will get the money and what is the money for are depended on the academic committee. In addition, the evaluation of scientific research results after completing the scientific research work and the research honor that those researchers care about most are also depended on the committee. That’s to say, you are working for it, but whether you will get the salary or bonus is up to them. However, they are not the boss. The boss is the CCP, they are only responsible for the technology. Because the boss wants to do the technical work without knowing the know-how, they are needed. In other words, the academic committee decides not only the allocation of the national full-funded special funds among the research groups in the national key laboratory, and also the research direction of each research group, and finally evaluated the research results and honors of the research group.

If you understand this, you will see at least three pieces of truth from the changes of the members of an academic committee:

  • A. Estimation of the extent of importance that CCP attaches and the fund
  • B. the research direction and the major subject direction of the laboratory
  • C. projection of the progress of the research
  • D. Others

Let ’s talk about A first. As you can see from the table above, the first session in 2005-2006 of this academic committee was composed of 6 academicians, 6 professors, and 4 researchers; the second session in 2011-2016 was 8 academicians, 5 professors and 4 researchers; the third session in 2017-2022 consists of 6 academicians, 5 professors, and 2 researchers. The importance of the laboratory research work can be seen from the number of academicians. The funds allocated by the CCP can be imagined.

Now B, from Guo Deyin’s statement, we can know that the laboratory chaired by Tian Bo is very important to the CCP, and many of the people related to Teacher Tian Bo are also associated with this committee, including Shu Hongbing, Wu Jianguo, and Hu Zhihong (Note: Here is not Chen Xinwen). This aspect explains that academician Tian Bo’s academic development control of this laboratory is based on virus research. Well, it can be seen from the titles of academic committee personnel that the core is virus research, because academicians direct the whole project and are academic authority, and they don’t work. Professors have to teach and may also work if they want. Therefore, the real people who do the major work are researchers. So, the chairman of the first committee was a student of Teacher Tian Bo, Wu Jianguo. The committee must include Hu Zhihong, the main force of the Wuhan Institute of Virology. Hu should also be a student of Tian Bo. Although Shu Hongbing and Teacher Tian Bo are not related to teacher-student, the relationship between them is also unusual (We can see it from the form disclosed by Guo Deyin earlier). His wife, Wang Yanyi, is a doctoral student of Mr. Tian Bo. It can be said that in the previous two academic committees, the research direction was firmly focused on the virus circle, so why did other academicians and scholars enter the academic committee? Outwardly, academicians and experts in academic committees are well-known people and scholars in this field, but the presence of Rao Zihe here is something else. The actual situation is that, as we disclosed in the previous article, this is the real core team for the development of viral weapons. Academician Tian Bo is performing a top-secret national mission or mission. Tian Bo ’s contribution even surpassed the older generation of scientists such as Qian Xuesen, and eventually allowed CCP to grasp the ultimate biochemical weapon. Therefore, the people who appeared in the previous two sessions were related to this task. It is not surprising that military representatives appeared. I predict that there will be more people who cannot appear in the academic committee. These people decide the research direction and cooperate to assist the action on the basis of the research progress of these two laboratories in Wuhan. Because this is not an individual behavior, but an organizational behavior. It is a collective behavior of the CCP on behalf of the whole country, and CCP needs them to collectively assume obligations and responsibilities.

Now C – Projection the progress of the research. Yes, it can be known from the changes in the personnel of the first, second, and third sessions of the committee. The first is the initial stage of the research, and the second is increased and adjusted by so many academicians (Note that the researcher did not adjust. Because the first stage of the research had achieved certain results or encountered a bottleneck, only then will it increase academic strength.) The major personnel replacement and the departure of key people of the third session of the committee should have two reasons; one is that the research work in 2016 has been basically completed, the other is that the construction work of the Wuhan P4 laboratory is next to completion. The task of this committee has basically been completed successfully. The main core forces have completed the strategic transfer and returned to normal laboratory research work.

Let ’s talk about D now. From the conclusions of the above and the form, we can be more certain that, although the swine fever in 2016 was not the same as the new coronavirus, both belong to coronavirus, and it is a coronavirus field test of biochemical weapons. It can be inferred that the swine fever coronavirus was produced in these two P3 laboratories in Wuhan, most likely the Shi Zhengli’s laboratory or Guo Deyin’s laboratory in Wuhan University. According to Miles Guo’s expose information, the production date was before the swine fever in October 2016. The swine fever virus is only a small part of the coronavirus biochemical weapon program. Behind it are hidden more research and plans of the coronavirus biochemical weapon, including the plan related to this new coronavirus. If this is the case, Academician Rao Zi, as deputy directors, should know the truth, and the laboratory of the Institute of Biophysics of the Chinese Academy of Sciences, which is led by him, is also engaged in related research work, so that the accidental death of Zhao Yongfang becomes logical after she accidentally knew the truth of the research work in the laboratory.

DT the Digger has revealed this list in the first season’s expose, and it tends to be interpreted as the result of political struggle, the struggle between the Jiang faction and the Xi faction, the Wang faction and the Jiang faction. Now it can be confirmed that CCP did it intentionally. The reason why now we can confirm is that, during the dig at that time, the key article written by Guo Deyin was noticed but the accidental death of Zhao Yongfang wasn’t, there were still many doubts to be dealt with.

The hype of the overseas propaganda of CCP proved the judgment of the DT the Digger. They tried to cover up the truth and suggested the personnel changes as a result of the political struggle, including Major General Chen Wei taking over the P4 laboratory.

In fact, in this form, the person who took over the P4 laboratory has already appeared, because this organization must be deeply involved in the virus development process, which is laid out from the beginning. On the day that the P4 will be built, this organization will take over the underground part of the P4 laboratory and the newly developed coronavirus, and will be ordered to mass-produce the virus in the P4 laboratory. At the same time, the over ground part of the P4 laboratory was taken over by the research force of the Wuhan Institute of Virology, which has completed the strategic transfer. It can be judged that it is the military force dominated by the Chinese Academy of Military Medical Sciences that takes over the P4 laboratory. The unit in charge is nominally the General Staff, in fact the Central Military Commission, and Major General Chen Wei is an academician of this Academy of Sciences. Therefore, the purpose of the Wuhan trip of Major General Chen Wei was not to take over the P4 laboratory in Wuhan. Otherwise, Guo Deyin, Shu Hongbing, Gao Fu, Wu Jianguo, and Hu Zhihong would not be as safe as they are now. The weird thing is that have you ever heard that people on this list have been infected with CCP virus?

Before continuing to tell this story, let us take a look at what Guo Deyin said: “In 2005, Wuhan University introduced Professor Shu Hongbing, an expert in cell biology, as the dean of the School of Life Sciences. Mr. Tian fully supported his research and even converted part of the office into a laboratory for his use and offered three graduate students to participate in his research. At the same time, all conditions of the Modern Virology Research Center are required to be open to Professor Shu’s research group.” Who are the three graduate students offered by Tian Bo? I am surprised if there is no special meaning, Guo Deyin will not remember so deeply!

One of the graduate students of Tian Bo is Xiao Gengfu, who is currently working at the Wuhan Virus Research Institute, and the other is Hu Zhihong, who is also currently working at the Wuhan Virus Research Institute. The other is Wang Yanyi. She studied at Wuhan University from September 2007 to June 2010 and obtained her doctorate. From December 2015, she served as the deputy director of Wuhan Institute of Virology, Chinese Academy of Sciences. She has served as director since October 2018. That is to say, one of the graduate students who provided Shu Hongbing with assistance was his wife at that time, event that shows the importance of Shu Hongbing’s new laboratory work. Regarding this sentence, my understanding is that Guo Deyin announced, “Everyone pays attention! The developer of the virus released later is Shu Hongbing and his family, not me Guo Deyin, hehe, this is evidence.”

Before telling the second story, we first list some materials to confirm the first story told.

List of management team of National Key Laboratory of Virology:

This list DT just revealed has also presented in season 1 and the previous article. The key is to look at the change of characters – the management team is the actual manager of these two laboratories whose main job is to manage specific research work and participate in research.

The list of 2005-2016 is the main force of research. Of course, Guo Deyin, Shu Hongbing, Wu Jianguo, Xiao Gengfu and Hu Zhihong will inevitably appear here. The management team manages two laboratories, on the one hand, Wuhan University, on the other hand, The Wuhan Institute of Virus Research. In regards of which one takes the lead, we can take a hint at the director and the deputy director. It is the laboratory of Wuhan University that ought to take the lead. That is, Wu Jianguo, Shu Hongbing and Guo Deyin are the leaders.

The change of the management team in 2016 is interpreted by many people that Jiang faction replaced Wang faction or other factions to take over the Wuhan virus laboratory. This is not a fact. The fact is that this team has transferred a strategic arrangement after completing the task of the organization.

That is to say, these key figures were all withdrawn from the management position of the “National Key Laboratory of Virology” at the end of 2016. Among them, Chen Xinwen and Hu Zhihong continued to work at the Wuhan Institute of Virology; Shu Hongbing and Wu Jianguo continued to teach at Wuhan University; Shu Hongbing continued management at Wuhan University; Guo Deyin and Chen Xinwen were promoted one after another. However, DT will ask, what is the purpose of the arrangement of Wang Yanyi, who is the wife of Shu Hongbing and proud disciple of Tian Bo, to succeed Chen Xinwen as the director of Wuhan Institute of Virology in October 2018? what is the purpose of the transfer of so many top scientists? The answer is obvious. On the one hand, the story of these two laboratories has been completed. To continue writing a story, the other purpose is that the weapon must be firmly in control!

Then, Wu Jianguo, a student of Academician Tian Bo. Take a look at his resume.

  • Bachelor’s degree in microbiology from Wuhan University in 1982.
  • Master’s degree in virology from Wuhan University in 1985.
  • A doctorate in biochemistry from the University of Idaho in 1992.
  • A postdoctoral fellow at Princeton University from 1993 to 1996.

He has successively worked at the academician Tian Bo laboratory of Institute of Microbiology of Chinese Academy of Sciences as replacing graduate student, the academician Miller laboratory of the University of Georgia as visiting researcher, the Professor Newton laboratory of the American Academy of Microbiology at Princeton University as researcher, the Doramas Institute as senior researcher, the US Sept Pharmaceuticals as consultant, and the Molecular Biology Laboratory of the Naval Health Research Center of the US Department of Defense as Director.

This low-key scientist like his teacher has a complicated American biomedical research experience. And he is a specially appointed professor of Changjiang Scholars by the Ministry of Education in 1999. He will appear in a later article.

Finally, other information implied in Guo Deyin’s article can be interpreted. This article by Guo Deyin is encrypted. He believes that someone in the distance must be able to discover and decrypt this encrypted article. The name of the person in the article is not casually presented, and the key person may not be presented, such as Mr. Tian Bo ’s three graduate students, because this is a mission of organization. If the article is not well written, they may be murdered by deliberately over-masturbating. There are still several photos in this article that were left out by DT the Digger, but one of the photos is shown here. Among the many photos that record the experiences with Mr. Tian Bo, Guo Deyin chose such a photo and noted: Visiting Tian Bo in the hospital. That’s meaningful. Let’s take a look at this photo: an old man who was seriously ill and about to die.

Here are some news reports about the demise of Mr. Tian Bo.

On December 15, 2019, Tian Bo, academician of the Chinese Academy of Sciences, researcher of the Institute of Biology of the Chinese Academy of Sciences, and professor of the University of the Chinese Academy of Sciences, died at the age of 88 because of ineffective medical treatment.
The farewell ceremony of Academician Tian Bo held – the Institute of Biology of the Chinese Academy of Sciences. December 19, 2019.
After the death of Academician Tian Bo, the leaders of the party and the state, Xi Jinping, Li Keqiang, Wang Qishan, Wang Chen, Chen Xi, Hu Jingtao, Wen Jiabao, Zhang Dejiang, Wu Guanzheng, Chen Zhu, Ding Zhongli, Xiao Jie, and Liu Yandong, expressed condolences to the death of the Academician Tian Bo, expressed condolences to their families, and presented wreaths. Leaders of the central and leaders of relevant national departments, Bai Chunli, Zou Xiaodong, and Li Shushen, and Academician Fang Rongxiang, Academician Wang Fusheng, Academician Rao Zihe, Academician Zheng Ruyong, Academician Gao Fu, Academician Xu Tao, Academician Shu Hongbing, Academician Yan Xiyun, Academician Xie Lianhui, and Academician Wei Chunjiang, expressed condolences to the death of the Academician Tian Bo, expressed condolences to their families, and presented wreaths. Central Organization Department, Central United Front Work Department, Chinese Academy of Sciences, Chinese Center for Disease Control and other units, Peking University, Tsinghua University, Chinese Academy of Sciences University, Wuhan University, Sun Yat-sen University and other universities and related colleges, China Academy of Inspection and Quarantine, many scientific research institutions such as the Institute of Biophysics of the Chinese Academy of Sciences, many associations such as the Chinese Society of Plant Pathology and the Chinese Society of Bioengineering, and many newspapers and publishing organizations such as the Chinese Science magazine have sent letters of condolences, flower baskets, wreaths, etc. Deep condolences to the death of Comrade Tian Bo.

Guo Deyin does not appear on this list because he is not yet an academician of the Chinese Academy of Sciences and is underqualified.

Shortly after Tian Bo’s death, coronavirus broke out in Wuhan. Wuhan, where is located Wuhan Institute of Virology that is in the charge of the beloved student of the father of Chinese virus research, was to sink into the raging of new coronavirus.

Well, the first story comes to an end, because the new management team of the P3 laboratory of Wuhan University and the new director are no longer important. Let us start the second story.

Before we start, let’s review some materials related to the first story.

The fourth meeting of the third academic committee of the National Key Laboratory of Virology was successfully held

Source: Virologica Chinese virology English version 2019-12-06

The academic committee members participating in this meeting include Academician Rao Zihe of Tsinghua University, Academician Shu Hongbing of Wuhan University, Academician Gui Jianfang of Wuhan Institute of Hydrobiology, Chinese Academy of Sciences, Academician Chen Hualan of Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Professor Xia Ningshao of Xiamen University, Professor Zhang Linqi of Tsinghua University, Researcher Chen Xinwen of Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, and Professor Lan Ke of Wuhan University. Academician Li Jiancheng, Vice President of Wuhan University, Researcher Xiao Gengfu, Secretary of the Party Committee and Deputy Director of Wuhan Institute of Virology, Chinese Academy of Sciences, and Professor Ke Tao, Dean of Science and Technology Development Institute of Wuhan University, attended the meeting. All PI of the laboratory attended the meeting. The meeting was chaired by the laboratory director Lan Ke.

At the meeting, Li Jiancheng and Xiao Gengfu made speeches on behalf of the laboratory-supporting-units respectively. Lan Ke reported to the Academic Committee the progress of the laboratory in 2019 in terms of operation management, representative achievements, team building, platform construction, and opening-up and communication. Lan Ke, Zhou Xi, Cui Zongqiang, Liu Shi and others respectively reported their latest research progress on virus-cell interaction and pathogenic mechanism and virus tracing research.

On June 19, 2017, the first plenary meeting of the Third Academic Committee of the National Key Laboratory of Virology was held in Wuhan University. The Academic Committee of the National Key Laboratory of Virology decides on the laboratory PI selection plan and the internal review of laboratory research project options. The new academic committee experts include: Academician Rao Zihe of Tsinghua University, Academician Wang Hongyang of Second Military Medical University, Academician Shu Hongbing of Wuhan University, Academician Gui Jianfang of Wuhan Institute of Hydrobiology, Chinese Academy of Sciences, Academician Wang Fusheng of PLA 302 Hospital, and Professor Yuan Zhenghong of Fudan University, Professor Zhang Linqi of Tsinghua University, Professor Xia Ningshao of Xiamen University, Researcher Chen Hualan of Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Researcher Zeng Musheng of Sun Yat-sen University, Professor Wu Jianguo of Wuhan University, Researcher Chen Xinwen of Wuhan Institute of Virology, Chinese Academy of Sciences, and Professor Lan Ke of Wuhan University. Academician Rao Zihe was appointed as the director of the Academic Committee. Academician Wang Hongyang and Academician Shu Hongbing were appointed as deputy directors.

Ministry of Science and Technology approved the establishment of the National Key Laboratory of Virology After the review by the Ministry of Education and the Ministry of Science and Technology, the National Laboratory of Virology jointly applied by Wuhan Virology Institute and Wuhan University Virus Institute overcome several problems, and finally won the approval of experts with strong strength. Recently, the Ministry of Science and Technology issued a document approving the official establishment of the National Virology Laboratory. The laboratory will make full use of the strengths of both parties to organically integrate related resources; through a series of measures such as attracting and training talents, it will further enhance its scientific and technological competitiveness and strive to carry out original research. Release date: Nov. 4, 2004
Ministry of Science and Technology approved the establishment of the National Key Laboratory of Virology in Wuhan Wuhan University and Wuhan Institute of Virology, Chinese Academy of Sciences have announced that the jointly applied National key virology laboratory has been approved by the Ministry of Science and Technology of China for preparation. According to the plan, the laboratory will be constructed for a period of one year from April 2005 to March 2006. At the seminar on the development strategy of the National Key Laboratory of Virology, held on April 16, Wu Jianguo, director of the laboratory and distinguished professor of Wuhan University, said that the laboratory will aim at the frontiers of virology research, focusing on AIDS, hepatitis viruses, influenza viruses, etc. Release date: Apr. 17, 2005
The Ministry of Science and Technology officially issued a document to approve the establishment of the National Key Laboratory of Virology In 2004, the National Key Laboratory of Virology, which was jointly applied by Wuhan Virology Institute and Wuhan University, was approved by review experts through many rounds of fierce competition. And according to the requirement, the report of the National Key Laboratory construction plan was submitted. After review by the Ministry of Science and Technology, the construction objectives stated in the report were clear, specific, and operable. On March 22, 2005, a document was formally approved to build the National Key Laboratory of Virology. Release date: Apr. 6, 2005
Science Journal published the research results of SARS of Chinese Academy of Sciences on Sep. 30, 2005 Beginning in March 2004, the joint research team collected sera, oral swab and anal swab samples of 408 bats from 3 families, 6 genera and 9 species in four areas: Guangxi, Hubei, Tianjin, Guangdong. The SARS virus antibodies and genes were simultaneously tested in the National Key Laboratory of Virology in Wuhan and the Animal Health Laboratory (AAHL) in Geelong, Australia. As a result, SARS virus antibodies and genes were found in 4 species. Release date: Sep. 30, 2005
Science and Technology Delegation of US Secretary of State visited Wuhan Institute of Virology The atmosphere of discussion with the leaders of relevant disciplines in the field is quite harmonious. Dr. George Atkinson also expressed his views at the meeting, and he was very grateful for the hospitality of the Wuhan Institute of Virology, hoping that the two sides can strengthen exchanges and cooperation between the two countries through communication and understanding. Under the leadership of Director Yuan, the delegation also visited the National Key Laboratory of Virology, the Biological Control Laboratory and the Viral Herbarium with great interest, and gave a high evaluation. Release date: Apr. 4, 2006
Pathology experts of School of Medicine of Case Western Reserve University visited Wuhan Institute of Virology After the report, under the leadership of Director Hu, the two visiting guests also visited the National Key Laboratory of Virology. Release date: May 13, 2006
The second seminar on emerging viral disease control closed The second seminar on emerging viral disease control came to an end at Wuhan Institute of Virology, Chinese Academy of Sciences. The conference was sponsored by the Chinese Academy of Sciences, undertaken by Wuhan Institute of Virology, co-hosted by the National Key Laboratory of Virology, School of Life Sciences of Wuhan University, Hubei Province Viral Disease Engineering Technology Research Center, Hubei Province and Wuhan Microbiological Society. Experts and scholars from home and abroad and graduate students of the institute participated in the meeting. Release date: Nov. 17, 2006
The first joint academic meeting of the National Key Laboratory of Pathogenic Microorganisms successfully held in Shiyan, Hubei Province Recently, the first joint academic meeting of the National Key Laboratory of Pathogenic Microorganisms was successfully held in Shiyan. The meeting was co-sponsored by the National Key Laboratory of Virology, the National Key Laboratory of Pathogen Microbiology Safety, and the National Key Laboratory of Infectious Disease Prevention and Control, and undertaken by the National Key Laboratory of Virology, in order to promote mutual exchanges between the three laboratories. Release date: Sep. 10, 2007
12 Nucleobases determine the life and death of experimental pigs: the construction of Shimen strain of swine fever virus and animal experiments Speaker Professor Zhang Chuyu, a doctoral supervisor, former deputy dean of the School of Life Sciences of Wuhan University, and dean of the Department of Virology. From Research Group of Virus Genetics and Molecular Evolution of the National Key Laboratory of Virology of Wuhan University Release date: Sep. 6, 2007
Dr. Peiyong Shi of the Wadsworth Center of the United States came to Wuhan Institute of Virology for academic exchanges and cooperation On the morning of the 15th, Dr. Shi listened to the academic reports of relevant students of the Institute of Virology and gave corresponding guidance. In the afternoon, he visited the National Key Laboratory of Virology and had a harmonious communication with relevant experts. Release date: June 23, 2008
The third seminar on emerging viral disease control held in Wuhan On October 28, The third seminar on emerging viral disease control, hosted by the Wuhan Institute of Virology, Chinese Academy of Sciences, the National Key Laboratory of Virology, Hubei Province and Wuhan Society of Microbiology, Wuhan Center for Viral Infectious Diseases, and the National Joint Research Institute, was closed. Release date: Oct. 31, 2008
Professor James M. Pipas of the University of Pittsburgh visited Wuhan Virology Institute Professor Pipas received his Ph.D. from Florida State University in 1975. He is currently engaged in the molecular biology of DNA tumor viruses and the molecular mechanism of tumorigenesis. Release date: Nov. 19, 2008
The fourth meeting of the first academic committee and academic exchange meeting of the National Key Laboratory of Virology was held in Wuhan On December 13, the fourth meeting of the first academic committee and academic exchange meeting of the National Key Laboratory of Virology was held in Wuhan, the meeting lasted two days. Release date: Dec. 16, 2008
Professor Lu Shan of the Medical School of University of Massachusetts visited Wuhan Institute of Virology After the meeting, Professor Lu Shan visited the National Key Laboratory of Virology and had a harmonious exchange with relevant teachers and students. He highly affirmed the research results obtained in my field. Release date: Mar. 26, 2009
Professor Hu Jianming of School of Medicine of Pennsylvania State University of the United States came to Wuhan Institute of Virology Professor Hu Jianming’s visit not only strengthened the academic exchanges between the researchers of Wuhan Institute of Virology and well-known foreign experts, but also laid a good foundation for the further cooperation between our institute and excellent foreign teams. Release date: Jul. 27, 2009
Professor of Drexel University visited Wuhan Institute of Virology On July 30, at the invitation of Xiao Gengfu, the deputy director of the Ntional Key Laboratory of Virology, Dr. Haitao Guo, assistant professor of School of Medicine of Drexel University and Pennsylvania Biotechnology Center, visited the Wuhan Institute of Virology, Chinese Academy of Sciences and made a wonderful academic report. Release date: Jul. 31, 2009
Scientists of our country synthesized new anti-viral compounds against Hanta virus The related papers of Yang Zhanqiu, director of the Institute of Medical Virology of Wuhan University and professor of the National Key Laboratory of Virology, were published in the recently published Chinese Pharmacology Journal. Release date: Aug. 3, 2009
Bai Chunli, executive deputy dean of the Chinese Academy of Sciences, visited the Wuhan Institute of Virology Bai Chunli, executive Deputy Dean of the Chinese Academy of Sciences, accompanied by Director of Wuhan Virology Institute, Chen Xinwen, visited the National Key Laboratory of Virology, cordially talked with scientific researchers and graduate students, learn about the progress of scientific research in detail, and gave encouragement to scientific researchers. Release date: Mar. 17, 2010
Hu Zhihong, researcher of Wuhan Institute of Virology, was selected as a national candidate for the New Century Ten Million Talent Project. Release date: Mar. 24, 2010
Lu Yongxiang visited Wuhan Branch Lu Yongxiang successively inspected the National Key Laboratory of Spectroscopy and Atomic and Molecular Physics of Wuhan Institute of Mathematics and Physics, the Key Laboratory of Frequency Standards Institute, the National Key Laboratory of Virology of Wuhan Institute of Virology, and the BSL-3 Laboratory, and listened the report on recent key work and future development ideas of various institutes. Release date: Apr. 13, 2010
The National Key Laboratory of Virology and Microbiology held a joint academic exchange meeting From April 9th to 11th, the first joint academic exchange meeting, jointly organized by the National Key Laboratory of Virology and the National Key Laboratory of Agricultural Microbiology, was successfully held in Xianning City, Hubei Province. Release date: Apr. 20, 2010
Cell Magazine published an article on the cooperation between the Wuhan Institute of Virology and American researchers to study the mechanism of non-enveloped dsRNA virus invasion and make new progress Scientists have been deeply studying the mechanism of membrane fusion of enveloped virus cells, but little is known about the mechanism of cell invasion of non-enveloped viruses. The main research direction of the aquatic virus and structure and function subject group, which belongs to the National Key Laboratory of Virology of Wuhan Institute of Virology, is focused on the research model of aquatic virus. Release date: May. 28, 2010
Professor Gao Shoujiang of the University of Texas visited Wuhan Institute of Virology for academic exchange Release date: Jun. 6, 2010
Liao Xiaohan, Deputy Director of the Basic Research Department of the Ministry of Science and Technology, visited Wuhan Institute of Virology In the following seminar, Xiao Gengfu, deputy director of the National Key Laboratory of Virology, and Wei Hongping, director of the Analytical Biotechnology Laboratory, reported on the research direction of the laboratory and the progress of scientific research. Release date: Jun. 21, 2010
The National Key Laboratory of Virology of Wuhan Institute of Virology held an academic exchange meeting From July 3rd to 4th, The National Key Laboratory of Virology of Wuhan Institute of Virology held an academic exchange meeting. The meeting was chaired by Xiao Gengfu, the executive deputy director of the key laboratory. Professor Guo Deyin, deputy dean of the School of Life Sciences of Wuhan University, leaders of the Wuhan Institute of Virology, Some key members of the laboratory, and the heads of management attended the meeting. Release date: Jul. 5, 2010
Dr. Rino Rappuoli of the Novartis company visited the Wuhan Institute of Virology After the meeting, Novartis and its party, accompanied by Researcher Shi Zhengli, visited the National Key Laboratory of Virology of Wuhan Virology Institute. Release date: Aug. 16, 2010
Significant progress has been made in the study of prion entry mechanisms Recently, the research team of Xiao Gengfu of the National Key Laboratory of Virology, and Professor Pang Daiwen of Wuhan University have made important progress in the study of prion entry mechanisms. Release date: Sep. 9, 2010
Wuhan Institute of Virology held the fourth seminar on emerging viral disease control From Oct. 24 to Oct. 27, the fourth seminar on emerging viral disease control, hosted by the National Key Laboratory of Virology and Wuhan Science and Technology Association, and undertaken by Wuhan Institute of Virology, Chinese Academy of Sciences, Hubei and Wuhan Microbiological Society, New Infectious Disease Center of Wuhan Institute of Virology, was successfully hold. Release date: Nov. 2, 2010
Dr. Zhou Tongqing , a HIV vaccine expert of USA, visited the Wuhan Institute of Virology Release date: Nov. 15, 2010
Virology experts of Wageningen University of Netherlands visited Wuhan Institute of Virology Release date: Nov. 19, 2010Wuhan Institute of Virology held the first joint seminar on viral structure and antiviral drugs The first joint seminar on viral structure and antiviral drugs, hosted by Wuhan Institute of Virology, the National Key Laboratory of Virology, Research Center for Major Infectious Diseases and Biosafety Network of Chinese Academy of Sciences, and undertaken by Laboratory of Molecular Virology and Bioengineering Technology of Wuhan Institute of Virology and Structural Biology Laboratory of Tsinghua University School of Medicine, was successfully held in Wuhan. The chairman of the conference is co-chaired by Academician Rao Zihe of Nankai University and Researcher Hu Zhihong of Wuhan Institute of Virology. Release date: Dec. 8, 2010
Professor Liang Zhiqing of the University of Hong Kong visited Wuhan Institute of Virology At present, the 454 ultra-high-throughput rapid detection system purchased by the National Key Laboratory of Virology is about to be put into use. The visit by Liang Zhiqing gave everyone a new understanding of high-throughput sequencing technology and also broke through the importance and necessity in related research. Release date: May 12, 2011
Dr. Lorone Babiuk, Vice President of the University of Alberta, Canada, visited the Wuhan Institute of Virology Release date: Jun. 6, 2011
Professor Lu Yuanan of the University of Hawaii visited Wuhan Institute of Virology Release date: Jun. 17, 2011
Dr. Ni Yi of Heidelberg University of Germany visited Wuhan Institute of Virology Release date: Jul. 1, 2011

Academician Tian Bo visited Wuhan Institute of Virology Release date: Jul. 12, 2011

The first East Lake Academic Forum and the Wuhan Virology Graduate Forum of 2012 successfully held After the on-site exchange, researcher Xiao Gengfu, the Assistant Director of Wuhan Virology Institute and the Deputy Director of the National Key Laboratory of Virology, made an academic summary, and put forward pertinent suggestions on the presentation form of the reporter, subject selection, and experimental design. Release date: Oct. 24, 2012
Wuhan Institute of Virology successfully held the fifth seminar on emerging viral disease control The conference was hosted by the National Key Laboratory of Virology, the International Cooperation Bureau of the Chinese Academy of Sciences, and the Wuhan Science and Technology Association. Release date: Oct. 30, 2012
Chen Xinwen Chen Xinwen, researcher, director of the Wuhan Institute of Virology, deputy director of the National Key Laboratory of Virology, a candidate for the Hundred Talents Program of the Chinese Academy of Sciences, and a recipient of the National Outstanding Youth Fund. He has obtained a bachelor’s degree from Huazhong Normal University and a master’s degree from Henan University of Technology, and a doctorate degree in virology from Wageningen University of Netherlands. He went to the University of California at Berkeley and Wageningen University of Netherlands to conduct cooperative research. Release date: Apr. 21, 2013
Hu Zhihong Hu Zhihong, researcher, deputy director of the National Key Laboratory of Virology, director of the Chinese Center for Viral Resources and Bioinformatics of Wuhan Institute of Virology, a candidate for the Hundred Talents Program of the Chinese Academy of Sciences, winner of the National Outstanding Youth Fund. He has obtained a bachelor’s degree from Wuhan University and a master’s degree from Wuhan Virus Research Institute, and a doctorate degree from Wageningen University of Netherlands. Release date: Apr. 21, 2013
Professor Jarvis Donald L of the University of Wyoming as a guest of Wuhan Institute of Virology Professor Jarvis Donald L is currently engaged in molecular biology research at the University of Wyoming. Release date: May 5, 2013
Incumbent leader Xiao Gengfu, born in 1966, Ph. D, researcher. He is currently the Secretary of the Party Committee, Deputy Director of the Wuhan Institute of Virology of Chinese Academy of Sciences, deputy director, deputy director of the National Key Laboratory of Virology, and leader of the viral biochemistry discipline group. Release date: Nov. 12, 2013
Wuhan Institute of Virology successfully held the fifth seminar on emerging viral disease control The conference was hosted by the National Key Laboratory of Virology, the International Cooperation Bureau of the Chinese Academy of Sciences, and the Wuhan Science and Technology Association. Release date: Mar. 11, 2014
American JCVI Institute held IRD / ViPR data training course at Wuhan Institute of Virology On July 11th, Professor Richard H. Scheuermann, Director of the Informatics Department of the JCVI Institute in the United States, was invited by Hu Zhihong, a researcher at the Wuhan Institute of Virology and the National Key Laboratory of Virology, to conduct IRD / ViPR database training at the Wuhan Institute of Virology. Release date: Jul. 21, 2014
Wuhan Institute of Virology held the sixth seminar on emerging viral disease control The meeting was hosted by the Wuhan Institute of Virology of Chinese Academy of Sciences. Release date: Nov. 7, 2014
Shanghai Pasteur Institute discovered type I interferon expression and new mechanism of anti-viral response The research was supported by the National Science and Technology Project 973, the National Natural Science Foundation of China, the Hundred Talents Program of the Chinese Academy of Sciences, and the National Key Laboratory of Virology. Release date: May 14, 2015
China Science Newspaper: Tian Bo, acute determination and splendid research for the public good Tian Bo, researcher of the Institute of Microbiology of Chinese Academy of Sciences. In 2001, he served as a professor of Wuhan University Academy of Sciences and the National Key Laboratory of Virology. Release date: Oct. 23, 2015
Professor Guo Deyin of Wuhan University invited by Ge Hong Forum Guo Deyin is currently a professor at the School of Life Sciences of Wuhan University, dean of Wuhan Basic Medical College, and deputy director of the National Key Laboratory of Virology. Release date: Dec. 12, 2015
Wuhan Institute of Virology held the 4th National Virology Graduate Forum In this forum, two experts were invited in the Ge Hong Forum of the Wuhan Institute of Virology -Professor Guo Deyin, the National Key Laboratory of Virology, and Researcher Jose Carlos Pastor-Pareja of the School of Life Sciences of Tsinghua University to give keynote speeches. Release date: Dec. 4, 2015
Three academicians of the Institute of Microbiology won the Lifetime Achievement Award of the Chinese Society of Plant Pathology Tian Bo, Researcher of the Institute of Microbiology of Chinese Academy of Sciences. In 2001, he served as a professor of Wuhan University Academy of Sciences and the National Key Laboratory of Virology. Release date: Aug. 18, 2016
Wuhan Institute of Virology held the 7th seminar on emerging viral disease control The meeting was hosted by the Wuhan Institute of Virology, the International Cooperation Bureau of the Chinese Academy of Sciences, and the Wuhan Science and Technology Association. Release date: Nov. 11, 2016
Researcher Hu Zhihong of Wuhan Institute of Virology won the honorary title of March 8th Red Flag Model Hu Zhihong, currently director of the China General Virus Collection Center, deputy director of the National Key Laboratory of Virology, director of the Center for Microbial Mycobacterium Species Resources and Applications of the Wuhan Institute of Virology, and former director of the Wuhan Institute of Virology. Release date: Mar. 7, 2017
The baculovirus successfully synthesized by the Wuhan Institute of Virology of Chinese Academy of Sciences Release date: May 2, 2017
Recruitment notice for senior laboratory engineer of animal infection model in Wuhan National Biosafety Laboratory (closed) The institute has a good academic environment and first-class research facilities. It has the National Key Laboratory of Virology, Wuhan National Biosafety (Level 4) Laboratory (Wuhan P4 Laboratory) and Asia ’s largest Chinese virus resource collection center. Release date: Jun. 22, 2017
New progress has been made in the study of malignant transformation of tumors caused by prion in Wuhan virus The research was funded by the National Natural Science Foundation of China, the pionerr A class project of the Chinese Academy of Sciences, and the National Key Laboratory of Virology. Release date: Sep. 18, 2017
Wuhan Institute of Virology has made significant progress in the study of the structure and function of baculovirus oxidase. This research was funded by the National Natural Science Foundation of China, the Strategic Leading Science and Technology Special Project of the Chinese Academy of Sciences, the 973 Project, and the Frontier Project in the National Key Laboratory of Virology. Release date: Sep. 19, 2017
Researcher Hu Zhihong of Wuhan Institute of Virology won the honorary title of March 8th Red Flag Model Hu Zhihong, currently director of the China General Virus Collection Center, deputy director of the National Key Laboratory of Virology, director of the Center for Microbial Mycobacterium Species Resources and Applications of the Wuhan Institute of Virology, and former director of the Wuhan Institute of Virology. Release date: Mar. 7, 2018
Mechanism of baculovirus O-glycosylation protein GP41 regulating virion assembly revealed by Wuhan Institute of Virology On April 12, Journal of Virology, a international academic journal, published the latest research results of the team of Wang Hualin of the National Key Laboratory of Virology. Release date: Apr. 17, 2018
Recruitment Notice of Wuhan National Biosafety Laboratory of Wuhan Institute of Virology of Chinese Academy of Sciences The institute has a good academic environment and first-class research facilities. It has the National Key Laboratory of Virology, Wuhan National Biosafety (Level 4) Laboratory (Wuhan P4 Laboratory) and Asia’s largest Chinese virus resource collection center. Release date: Apr. 18, 2018
Recruitment notice for the head of infrastructure of the Comprehensive Office of Wuhan Institute of Virology The institute has a good academic environment and first-class research facilities. It has the National Key Laboratory of Virology, Wuhan National Biosafety (Level 4) Laboratory (Wuhan P4 Laboratory) and Asia ’s largest Chinese virus resource collection center. Release date: Jan. 17, 2018
Concentrated recruitment notice of the fourth quarter of 2017 of Wuhan Institute of Virology (closed) The institute has a good academic environment and first-class research facilities. It has the National Key Laboratory of Virology, Wuhan National Biosafety (Level 4) Laboratory (Wuhan P4 Laboratory) and Asia ’s largest Chinese virus resource collection center. Release date: Nov. 1, 2017
Concentrated recruitment notice of the third quarter for scientific research positions of Wuhan Institute of Virology (closed) The institute has a good academic environment and first-class research facilities. It has the National Key Laboratory of Virology, Wuhan National Biosafety (Level 4) Laboratory (Wuhan P4 Laboratory) and Asia ’s largest Chinese virus resource collection center. Release date: Aug. 1, 2018
Recruitment notice for the Comprehensive Office of the Wuhan Institute of Virology (closed) The institute has a good academic environment and first-class research facilities. It has the National Key Laboratory of Virology, Wuhan National Biosafety (Level 4) Laboratory (Wuhan P4 Laboratory) and Asia ’s largest Chinese virus resource collection center. Release date: Oct. 16, 2016

The second story about two labs

The second story about two labs began with SARS in 2003. First of all, we excerpt some materials.

Academician Lu Yongxiang instructed the Chinese Academy of Sciences to concentrate strength on further fighting against SARS

Renovate relevant laboratories and start basic research work on virus prevention. The Institute originally only studied viruses other than those of humans. In the face of SARS viruses, it urgently transformed and built a P3 laboratory, launched a P4 laboratory transformation plan, introduced live viruses for experiments, and made long-term hard work and preparation for understanding and preventing SARS.

The Beijing Institute of Genomics has collaborated with the Academy of Military Medical Sciences to complete the gene sequencing of four groups of SARS viruses. The sequencing results have found mutation behaviors. Samples are being added to find the law of virus mutations. Two virus detection methods, enzyme-linked kit and PCR antigen test, were urgently developed to achieve early diagnosis and confirmation, and can be supplied in batches soon. Beijing Genomics Research Institute, Institute of Microbiology and Shanghai Institute of Life Sciences are stepping up the development of vaccines and effective drugs. The Shanghai Institute of Organic Medicine, the Institute of Medicine and the Kunming Institute of Animal Science searched for antiviral drugs based on the screening of hundreds of existing compound drugs. In addition, some long-term research work aimed at developing effective drugs has also been initiated. Third, renovate relevant laboratories and start basic research work on virus prevention. The Institute originally only studied viruses other than those of humans. In the face of SARS viruses, it urgently transformed and built a P3 laboratory, launched a P4 laboratory transformation plan, introduced live viruses for experiments, and made long-term hard work and preparation for understanding and preventing SARS. At the same time, the Kunming Institute of Zoology and the Shanghai Research Institute, together with the Academy of Military Medical Sciences, with the support of the General Logistics Department of the PLA, organized the establishment of a higher animal research center to use primates for virologic experiments. The Institute of Animal funds themselves and conducts research on finding the source of pathogens in Guangdong.

In this report, there are several key messages.

1. “The Beijing Institute of Genomics has collaborated with the Academy of Military Medical Sciences to complete the gene sequencing of four groups of SARS viruses. The sequencing results have found mutation behaviors. Samples are being added to find the law of virus mutations.” Note that this shows that they sampled the strains of SARS virus and completed the genetic sequencing of 4 groups of SARS virus, and they still increased samples. The SARS coronavirus sampling task should be the work of the Academy of Military Medical Sciences, and the sequencing should be the work of the Beijing Genomics Institute.

2. “The Shanghai Institute of Organic Medicine, the Institute of Medicine and the Kunming Institute of Animal Science searched for antiviral drugs based on the screening of hundreds of existing compound drugs.” Ostensibly, these three units are responsible for drug screening for antiviral drugs. In fact, no drugs have been found to treat SARS, so their real purpose is to do some experiments. Therefore, some long-term research work aimed at developing effective drugs has also been initiated. The most important thing is the following paragraph – Kunming Institute of Zoology and Shanghai Research Institute together with the Academy of Military Medical Sciences, with the support of the General Logistics Department of the PLA, organized the establishment of a higher animal research center to use primates for virologic experiments. Here comes again the Academy of Military Medical Sciences, and with the support of the General Logistics Department of the PLA, a higher animal research center was established in Kunming, using primates to conduct virologic experiments. That means to establish the world ’s largest monkey virus experimental base in Kunming. This base is a military restricted area and a confidential unit. At that time, virologic experiments of SARS coronavirus on live monkeys had been conducted.

3. “The Institute of Animal funds themselves and conducts research on finding the source of pathogens in Guangdong.” This animal institute does not refer to the Kunming Animal Institute, but is an abbreviation within the Chinese Academy of Sciences. It is the Institute of Zoology of the Chinese Academy of Sciences. This unit is responsible for finding the mother of the virus, that is, to find the source of the virus. The aim is to prove that the virus originates from nature. This institute will be mentioned later.

4. “Renovate relevant laboratories and start basic research work on virus prevention. The Institute originally only studied viruses other than those of humans. In the face of SARS viruses, it urgently transformed and built a P3 laboratory, launched a P4 laboratory transformation plan, introduced live viruses for experiments, and made long-term hard work and preparation for understanding and preventing SARS.” The institute here refers to the Wuhan Institute of Virology of Chinese Academy of Sciences. Here, the P4 laboratory appeared for the first time. The Wuhan Institute urgently built the P3 laboratory, launched the P4 laboratory transformation plan, and introduced live viruses for experiments. Pay attention to this sentence. In other words, the introduction of live viruses means that the source and collection of live viruses and the search for the host are not its job. The live virus come from the Academy of Military Medical Sciences, and the P4 laboratory prepared for the condition for doing long-term hard work to understand and prevent SARS virus.

Here is the list of allocation of SARS virus research in the above units.

In other words, during SARS as early as in 2003, the Wuhan Institute of Virology established a P3 laboratory and started the transformation plan of the P4 laboratory on the basis of it. In the previous article, we know that it is not necessary to use a P4 lab to study SARS coronavirus. That the Wuhan Institute of Virology initiated the plan to transform P4 laboratory is obviously not to study coronavirus. It is not easy to understand for people who does not understand biological virus research. So, everything becomes reasonable and logical because of SARS epidemic. If it were not for scientists to help us interpret some basic knowledge and concepts, perhaps we will never understand this.

The second story is the story of two laboratories, one P3 laboratory and the other P4 laboratory.

The first scene in the beginning of the story is that a famous female scientist did a job that was not her division of labor – to find the source of the coronavirus. According to the division of labor, this work is the responsibility of the Institute of Zoology of Chinese Academy of Sciences.

Let’s take a look at all the reports that we can find out about the source of coronavirus.

1. Source of SARS virus released on September 29, 2005

Chinese scientists found that bats carry SARS-like viruses — scientists of Chinese Academy of Sciences, collaborated with foreign experts, made new breakthroughs in the study of SARS virus animal traceability

The results of a joint study conducted mainly by scientists from the Chinese Academy of Sciences showed that bats carry SARS-like viruses. The results of this study were published in Science on September 29, 2005.

As we all know, the 2002-2003 SARS outbreak affected 26 countries and regions, causing more than 8,000 infections and 774 deaths. A new coronavirus was identified as the pathogen of SARS. In the process of animal traceability of SARS virus, early research results proved that civet cat may be the natural host of SARS virus.

A joint research team composed of Shi Zhengli, a researcher at the Institute of Virology, Chinese Academy of Sciences, and Zhang Shuyi, a researcher at the Institute of Zoology, and other scientists paid attention to the research: In recent years, bats have been proven to be natural hosts of some important animal-borne infectious disease virus pathogens (both humans and animals can be infected), and these virus-infected bats basically have no clinical symptoms. Therefore, the joint research team focused on the tracing of SARS virus in bats.

Since March 2004, the joint research team has collected serum, oral swab and anal swab samples of 408 bats from 3 families, 6 genera and 9 species in four regions: Guangxi, Guangdong, Hubei and Tianjin. The SARS virus antibodies and genes were simultaneously tested in the National Key Laboratory of Virology in Wuhan and the Animal Health Laboratory (AAHL) in Geelong, Australia. As a result, SARS virus antibodies and genes were found in 4 species of Rhinolophus sinicus genera, among which Big-eared horseshoe bat showed over 70% of antibody positive rate. Gene sequence analysis showed that the genome sequence homology of bat SARS virus and human SARS virus reached 92%. However, the difference between the two plays a key role in whether the bat SARS virus can spread across species, that is to say, the SARS virus detected by scientists in bats will not directly infect humans.

This paper is the first paper to look for coronavirus in bats after SARS outbreak. It is very simple. First catching bats, then using molecular biology to detect SARS-like viruses. As a result, bats are a natural biological and chemical weapons arsenal. However, Shi Zhengli is also the first author of this paper. Generally speaking, the first author of a paper is the one who do the work, and the following author is the planner and boss. This paper made Shi Zhengli unstoppable and started her career as an independent researcher in the development of biochemical weapons at the Wuhan Institute of Virology.

2 Source of SARS virus

Nature: Research confirms that SARS virus is derived from Rhinolophus sinicus
The international research team led by researcher Shi Zhengli of the Wuhan Institute of Virology, including Ecohealth Alliance, Australian Animal Health Laboratory, One Health Institute, School of Veterinary Medicine, University of California, Davis, East China Normal University, and Duke-NUS Graduate Medical School, Singapore isolated a SARS-like Coronavirus that is highly homologous to SARS virus, a event that further confirmed that the Rhinolophus sinicus bat is the source of SARS virus.

By the time this paper was published, Shi Zhengli had already been promoted to a researcher at the Wuhan Institute of Virology. In the thesis, the research team led by Shi Zhengli claimed that the virus that can infect human naturally was discovered in bats. However, we have already analyzed in the previous article that the so-called bat virus isolated by Shi Zhengli shows a characteristic of the recombination of SARS virus and bat virus. Therefore, we infer that the virus was man-made by Shi Zhengli in the laboratory, and the purpose that Shi Zhengli said it was from a natural virus in bats is to wash away the biological and chemical weapons and pave the way for the future use.

From Guangming Daily. Scientists confirm that SARS virus was originated from Rhinolophus sinicus. Journalist Qi Fang learned from the Chinese Academy of Sciences that an international research team led by Shi Zhengli, a researcher at the Wuhan Institute of Virology, Chinese Academy of Sciences, isolated a SARS-like coronavirus highly homologous to SARS virus, further confirming that the Rhinolophus sinicus is the source of SARS virus. The internationally renowned academic journal Nature published this result on the 31st. The research team published a paper on Science in 2005 that it found that “bats are natural hosts for SARS-like coronavirus.” Release date: Nov. 1, 2013

3 Sources of swine fever virus in 2016. Published in 2018

Scientists discovered a new coronavirus derived from bat Source: XinhuaNet Apr. 5, 2018

Regarding the three viruses discovered and analyzed by the team of Shi Zhengli, let us make a brief table.

Expert Reviews:

The coronavirus that caused swine fever in 2016 is a virus very similar to the coronavirus HKU2 found in bats in the laboratory of Yuan Guoyong of the University of Hong Kong. In this paper,

Research by Shi Zhengli and collaborators showed that the overall similarity of the swine fever coronavirus and Yuan Guoyong team’s coronavirus HKU2 found in bats reached 95%. The similarity of S protein is 86%. This similarity makes people suspect that the 2016 swine fever virus was artificially modified or recombined from coronavirus HKU2 of 2007. Although the receptor used by the swine fever coronavirus to invade cells is unclear, the swine fever virus is likely to be the result of the S protein modification or artificial recombination through forward genetics. The whole swine fever virus is an animal experiment of a coronavirus outbreak.

In general, it is difficult to trace the source of natural virus. But Shi Zhengli claimed in the article that he found a coronavirus with a 98% similarity to the swine fever virus in the bats in the cave next to the swine fever outbreak area. Why is it so coincident every time, no matter what coronavirus breaks out, Shi Zhengli can find a very similar virus on the bat and publish an article in the international top scientific magazine Nature. This is the case for swine fever virus, so is the CCP virus. How can other scientists not encounter such a good thing? Therefore, bats are an omnipotent reason for the CCP’s wash-away of biological and chemical weapons. No matter what virus is tested, as long as another paper is published saying that similar viruses are found in nearby bats, the CCP’s biological and chemical weapons can be washed away.

Through Shi Zhengli’s several trips to discover viruses, we should know what the job of two laboratories of Wuhan Institute of Virology are.

Conclusion: The P3 laboratory develops viruses, and the P4 laboratory is a manufacturer producing viral weapons and can develop higher-level virus weapons.

Let’s continue to read some information about this story.

Li Changchun listened to the report on the progress made by Wuhan Institute of Virology against SARS Brief report to Li Changchun and other leading comrades on the research direction and important achievements of the institute, the formation of the SARS research expert group and the progress of the work, and the progress of active participation in the launch of the SARS emergency project, P3 laboratory construction and P4 laboratory preparation in the Chinese Academy of Sciences and Hubei Province. Release date: May 15, 2003 Note: In May 2003, Li Changchun (the then Politburo Standing Committee) listened to the preparation of the P4 laboratory and the construction of the P3 laboratory. Yu Zhengsheng , Secretary of Hubei Provincial Party Committee, attended the report meeting.
Chen Zhu emphasized that taking P4 laboratory construction as an opportunity to form a new mode of preventive medicine operation On May 28th, Academician Chen Zhu, Vice President of the Chinese Academy of Sciences, had a discussion with Wuhan Mayor Li Xiansheng, Vice Mayor Hu Shuguang and other leaders to build the P4 laboratory in Wuhan, and reached an agreement. Release date: Jun. 1, 2003
Leaders of Hubei Province Meet with Academician Chen Zhu, Vice President of Chinese Academy of Sciences The two sides exchanged views on the current fight against SARS, the construction of the P4 laboratory in Wuhan and the cooperation between Hubei Province and the Chinese Academy of Sciences, and formed consensus. Release date: Jun. 1, 2003
Professor Zhang Jingqiang: SARS breakthrough is the matter that is most concerned about on account of being left behind by others Xie Qi said that because there is no P4 laboratory and lack of due experimental conditions in China, virus research is relatively weak But the European Community National Bioengineering Research Center led by the SARS project has good laboratory conditions. There are only a few P4 laboratories in the world. Release date: Jun. 5, 2003

Note: Xie Qi, the project coordinator of P4 Laboratories in Europe, comes to surface.

Xie Qi, Ph.D., researcher, doctoral supervisor.

Bachelor of Sun Yat-Sen University in 1987.

Master degree of Guangdong Institute of Microbiology in 1990.

Doctor degree of Universidad de Madrid University in Spain in 1994.

From 1995 to 1998, he continued his postdoctoral work at Universidad de Madrid and Rockefeller University in the United States. In 1998, he was hired as Research Fellow at the School of Molecular Agricultural Biology, National University of Singapore, and later as the Executive Director of the Plant Cell Research Office of the School. He was Executive Director (Acting Principal Investigator) of Molecular and Cell Research of Temasek Life Sciences Laboratory, National University of Singapore before returned to China. Since 2002, he has been the Distinguished Professor of Yangtze River Scholars in the School of Life Sciences of Sun Yat-sen University. He was the winner of the 2003 National Outstanding Youth Science Fund. In 2004, he was selected as the “Hundred Talents Program” of the Chinese Academy of Sciences. In 2008, he was approved by the State Council as an expert privileged special government allowance. Now he is the chief scientist of the National Major Scientific Research Program-Plant Protein Modification and Degradation Research Project.

Vice President Bai Chunli visited Wuhan Institute of Virology He sincerely hopes that scientific researchers will seize the opportunity and work hard to occupy an irreplaceable position in the national research field, especially through the construction of P3 and P4 laboratories to provide a technical platform for national research and become a communication center. To supplement research funding, enhance the status of research institutes, and train scientific and technological teams through fighting for major national projects. Release date: Jul. 9, 2003
Chen Zhu, Vice President of the Chinese Academy of Sciences and Hu Zhihong, Director of the Wuhan Institute of Virology, visited France From July 16 to 19, Chen Zhu, Vice President of the Chinese Academy of Sciences, Hu Zhihong, Director of the Wuhan Institute of Virology, and other representatives visited France in terms of emerging diseases research and laboratorial cooperation. Release date: Jul. 23, 2003
Chinese Academy of Sciences and Wuhan City jointly build China’s first Biosafety Level 4 laboratory Hu Zhihong, Director of Wuhan Institute of Virology, delivered a speech first, thanking the Chinese Academy of Sciences and the leaders of Wuhan City for attaching great importance and cordial care to the construction of P4 laboratory. Release date: Jul. 24, 2003
Chen Zhu, Vice President of the Chinese Academy of Sciences, met with Li Xiansheng, the Mayor of Wuhan Vice President Chen Zhu thanked the Wuhan Municipal Government for its support and assistance to the Chinese Academy of Sciences in building the P4 laboratory in Wuhan. Release date: Jul. 28, 2003
Chinese Academy of Sciences strengthened cooperation with French science and technology community Academician Chen Zhu met, at the Shanghai Academic Activity Center of the Chinese Academy of Sciences, with a French emerging disease cooperation team composed of the consultant of the French Minister of National Research and New Technology Office, the director of the Pasteur Institute of Paris, and the director of the P4 laboratory of Merrill. Release date: Mar. 15, 2004
Domestic Ebola vaccine research and development need 5 to 10 years The reporter was informed that China is still actively constructing the P4 laboratory necessary to study Ebola virus. Release date: Aug. 14, 2004
From Xinhua Net: Our country has built the first P4 laboratory with the highest level of biological safety protection Our country’s first laboratory with the highest level of biosafety protection-Wuhan National Biosafety Laboratory (Wuhan P4 Laboratory), Chinese Academy of Sciences, was completed on January 31 in Wuhan, Hubei. Release date: Jan. 31, 2015
The French Ambassador to China awarded Yuan Zhiming and Shi Zhengli of Wuhan Institute of Virology On behalf of the French government, Gu Shan thanked Yuan Zhiming, Shi Zhengli and his team for their outstanding contributions to promoting cooperation in the prevention and control of emerging infectious diseases between China and France, as well as in the construction of the Wuhan P4 laboratory in China-France cooperation. In recent years, China and France have cooperated closely on the construction of Wuhan P4 laboratory, in the construction of biosafety laws, regulations and standards, the research on the prevention and control of emerging infectious diseases, and personnel training. Release date: Jun. 17, 2016
French Prime Minister Bernard Cazeneuve visited P4 laboratory of Wuhan Institute of Virology, Chinese Academy of Sciences On the morning of February 23, the French Prime Minister and his party visited Wuhan, Hubei, and visited in the first place the P4 laboratory of the Wuhan Institute of Virology, Chinese Academy of Sciences. Release date: Feb. 23, 2017
From China Youth Daily: aircraft carrier of our country’s life sciences P4 laboratory will be officially launched soon As the first P4 laboratory in China, the Wuhan National Biosafety Laboratory of the Chinese Academy of Sciences has made the latest progress. The reporter learned from the Wuhan Institute of Virology, Chinese Academy of Sciences on February 23 that after more than a year of trial operation, Wuhan P4 Laboratory has now obtained the laboratory accreditation certificate from China National Accreditation Service for Conformity Assessment. In the near future, the laboratory will be officially put into operation. Release date: Feb. 24, 2017
Xu Nanping, Deputy Minister of Science and Technology, investigated the Wuhan Institute of Virology On the afternoon of April 26, Xu Nanping, a member of the Party Leadership Group of the Ministry of Science and Technology, and his entourage investigated the Wuhan Institute of Virology, Chinese Academy of Sciences. Xu Nanping and his party visited Wuhan National Biosafety Laboratory (Wuhan P4 Laboratory) to learn more about the construction process, functional layout, operation status, certification and approval, and biosafety management system construction of Wuhan P4 Laboratory, and communicated with the laboratory team. Release date: Apr. 28, 2017
Party Secretary Zhang Shengren of Hubei Science and Technology Department investigated Wuhan Institute of Virology Zhang Shengren and his entourage visited the Wuhan National Biosafety Laboratory (Wuhan P4 Laboratory) to learn more about the construction process, functional layout, operation status, certification and accreditation, and biosafety management system construction of Wuhan P4 Laboratory. Release date: Jun. 6, 2017
Liu Yandong met with Chairman of the French Mérieux Foundation Liu Yandong spoke highly of the positive contributions made by the foundation, especially contributions that was made by the China-France P4 laboratory to strengthen cooperation between population health and public health and promote China-France friendship. Release date: Nov. 25, 2017
ZhangJie investigated the CAS-MPG Partner Institute for Computational Biology (PICB) and Shanghai Pasteur Institute Wuhan Institute of Virology has established a close strategic partnership to truly achieve open sharing with Wuhan P4 Laboratory, and to play an important scientific and technological support role in the field of public health. Release date: Dec. 12, 2017
China’s first P4 laboratory is officially in operation, dedicated to the most dangerous virus research The Science and Education Department of the National Health and Family Planning Commission recently learned that the Wuhan National Biosafety Level 4 Laboratory of the Chinese Academy of Sciences has passed the on-site assessment of the pathogenic pathogenic microbial experimental activities of the National Health and Family Planning Commission, officially becoming the first to put into operation in China’s P4 laboratory. Release date: Jan. 5, 2018
The new French Ambassador to China Li Xiang visited Wuhan Institute of Virology Wang Yanyi, deputy president of Wuhan Institute of Virology, met with Li Xiang and his party, and Yuan Zhiming, director of Wuhan P4 Laboratory, accompanied the meeting. Release date: Mar. 26, 2018
ZhangJie visitd France and Italy During his visit to France, Zhang Jie visited INSERM as the chairman of the Chinese-French emerging infectious disease prevention and control cooperation, and held a meeting with the French chairman and INSERM president Ives Levy. The two sides reached consensus on strengthening the connection between Wuhan P4 Laboratory and related European networks and cooperation between the two sides in the African region. Release date: Apr. 19, 2018
Wuhan National Biosafety Laboratory passed the process acceptance On May 9, the process acceptance meeting of Wuhan National Biosafety Laboratory (Wuhan P4 Laboratory) of Chinese Academy of Sciences was held at Wuhan Institute of Virology, Chinese Academy of Sciences. Release date: May 16, 2018
The establishment meeting and also the first meeting of the Scientific and Technical Steering Committee of Wuhan National Biosafety Laboratory of Chinese Academy of Sciences held On the morning of September 29, the establishment meeting and also the first meeting of the Science and Technology Steering Committee of Wuhan National Biosafety Laboratory (Wuhan P4 Laboratory) of the Chinese Academy of Sciences was held in Wuhan. Zhang Tao, vice president of the Chinese Academy of Sciences and member of the party group, attended the meeting. The meeting was chaired by Gao Fu, academician of the Chinese Academy of Sciences and director of the Wuhan P4 Laboratory Technology Steering Committee. Release date: Sep. 30, 2018
The Party Branch of Zhengdian Laboratory: Keep in mind the responsibilities, stick to the mission, and be a pioneer in the field of high-level biosecurity The Party branch of the Zhengdian Laboratory of the Wuhan Institute of Virology, Chinese Academy of Sciences is the main force in the construction of the Wuhan National Biosafety Laboratory (Wuhan P4 Laboratory) of the Chinese Academy of Sciences. Release date: Nov. 8, 2018
The construction project of Wuhan National Biosafety Laboratory of Chinese Academy of Sciences passed acceptance On November 27, the construction project of Wuhan National Biosafety Laboratory (Wuhan P4 Laboratory) of the Chinese Academy of Sciences passed acceptance. Release date: Nov. 30, 2018
Wuhan Institute of Virology made progress in establishing a biosafety level 4 laboratory staff training system In 2018, China’s first level 4 biosafety laboratory — Wuhan National Biosafety Laboratory (Wuhan P4 Laboratory) of the Chinese Academy of Sciences was officially put into operation. Establishing a comprehensive and complete biosafety training system is a necessary condition and an important guarantee for effectively preventing biosafety accidents and ensuring the safe, stable, and efficient operation of laboratories. Release date: Apr. 23, 2019

From the above information, we know that the address of the Wuhan National Biosafety Laboratory of Chinese Academy of Sciences of Wuhan Institute of Virology, also Wuhan P4 Lab, is located in Zhengdian, and the Party Branch of Zhengdian Lab of Wuhan Institute of Virology is responsible for the construction work.

  • The construction of the laboratory started in July 2003.
  • Completed on January 31, 2015.
  • On February 24, 2017, after more than a year of trial operation, the certification was obtained, that is to say, the date of the trial operation was in early 2016.
  • Officially launched in January 2018.
  • Passed the process acceptance on May 16, 2018.
  • Accepted on November 31, 2018.

Above all, Wuhan P4 Lab has been called Zhengdian Lab during the construction process, and the person in charge is Yuan Zhiming, currently the party secretary and deputy director of Wuhan Institute of Virology. He used to be the former director of Zhengdian Laboratory.

At the end of 2015, Zhengdian Lab publicly released recruitment notices.

The following deeds published on the Chinese Academy of Sciences website give us more information on P4 experiment management.

The Party Branch of Zhengdian Laboratory: Keep in mind the responsibilities, stick to the mission, and be a pioneer in the field of high-level biosecurity.

Release time: Nov. 8, 2018 Source: Wuhan Institute of Virology

The Party branch of the Zhengdian Laboratory of the Wuhan Institute of Virology, Chinese Academy of Sciences is the main force in the construction of the Wuhan National Biosafety Laboratory (hereinafter referred to as “Wuhan P4 Laboratory”) of the Chinese Academy of Sciences. The party branch of Zhengdian Laboratory currently has 16 party members, accounting for 57% of the total number of laboratory construction teams. In the construction team of Zhengdian Laboratory, there are 7 deputy senior and above personnel, all of whom are members of the Communist Party of China. For many years, under the leadership of the Party Committee of the Institute, the party branch of Zhengdian Laboratory, which is led by ideological construction, combined the particularity of the work undertaken, promoted the construction of the laboratory with “four best efforts”, and effectively played the role of battle fortress in the construction of Wuhan P4 laboratory.

1. Leading by thoughts and using ideals and beliefs to unite

In 2003, SARS raged. The country required Wuhan Institute of Virology to undertake the task of building a Wuhan P4 laboratory from a strategic perspective. At that time, domestic scientists knew little about this laboratory of the highest level of biosecurity. Wuhan Institute of Virology was in a “three Nos” situation: no equipment and technical standards, no design and construction team, no Ph.D. Facing the needs of the country, we had the courage to undertake the construction tasks of the P4 laboratory, and immediately set up the construction team of the Zhengdian laboratory. Facing the endless unknown, the challenges can be imagined.

Ideals and beliefs are the spiritual calcium, which is the source of motivation to carry out scientific research. The party branch of Zhengdian Laboratory played a leading role in thinking, adhered to the “three sessions and one lesson” system, and took the “two studies and one do” learning and educational activities as the carrier to earnestly study the spirit of the 19th National Congress of the Party and of important speeches of the general secretary Xi Jinping when he inspected our institute, ideologically guiding party members to establish the ideal and belief of innovating technology, serving the country, and benefiting the people. Especially in 2017, the Party Branch and Subcommittee of Zhengdian Laboratory carefully planned and organized the activity of Casting the Ideal into Reality-My Position in the Team, focusing on the ideals and beliefs of each party member. In this activity, the party branch selected three party members of different ages, in the form of looking back and going forward, to guide young party members to think from a farther perspective and a higher angle to adhere to ideal and belief and practice a life without regret. At the same time, let each party member clearly understand the lofty significance of their positions, and realize that ordinary positions can also do extraordinary work, thereby further inspiring the work enthusiasm of party members and comrades. In actual work, comrades of party members have played a more active role and contributed to the development of multiple work links such as technological innovation, management innovation, and detail improvement. This makes the operation and maintenance of facilities more efficient, more stable, and more constructive for the operation and management of laboratories.

At the same time, the party branch of Zhengdian Laboratory attaches great importance to team capacity building, and expands meetings through branches to discuss the project implementation and technical issues. On this platform, you can talk about the experience in equipment management or the puzzles you encounter. Through expressing your opinions, sharing your experiences, and discussing together, you can solve problems, accumulate experience, improve capabilities, and effectively promote the construction and operation of the laboratory.

2. Undertaking the mission and playing the exemplary role of party members as pioneers

In the process of building the Wuhan P4 laboratory, the construction team of the Zhengdian laboratory experienced one challenge after another, including imperfect construction and design standards, insufficient investment estimates, long construction cycles, large changes in the policy environment, and updated national standards. Song Donglin, deputy director of Wuhan P4 Laboratory and party member of Zhengdian Laboratory, is the core backbone of the biosafety system. After one year of trial operation of the P4 laboratory, Song Donglin led his team to write the complete management system documents of 500,000 words, including the Biosafety Management Manual, procedure documents, Standard Operating Procedure (SOP), record forms and risk assessment reports, providing a solid guarantee for the safe and efficient operation of the laboratory. Tong Xiao, Secretary of the Party Branch of Zhengdian Laboratory, is the technical person in charge of the construction of Wuhan P4 Laboratory and the chief commander of the project. 2015 was the year of his son’s college entrance examination and the key debugging period of the laboratory. In order to put the laboratory into use as soon as possible, he devoted himself to the exploration of debugging problems without taking into account the needs of his family. “Personal difficulties can always find a way to overcome, but the delay of the laboratory’s debugging progress will cause losses to the research institute and adversely affect scientists,” he said.

3. Pioneering and innovating, promoting the voyage of the aircraft carrier of P4 laboratory with four best efforts

The team of Zhengdian Laboratory has increased from the 3 people in the beginning to 28 people. Droves of outstanding young talents have continuously joined this large family, and the “diligence, dedication, due diligence and responsibility” proposed by the party branch of Zhengdian Laboratory has become a magic weapon for the team to achieve professional. Make every effort to improve professional ability, work level, efficiency effect; try to face technical problems, coordinate and solve all kinds of difficulties; do AB post work diligently and become a master in the professional field; invest in the work with the sense of responsibility of the owner. Since China lacks of experience in construction and maintenance of P4 laboratories, the laboratory mainly introduces design and key equipment through Sino-French cooperation. After digestion, absorption and re-innovation, the laboratory construction meets domestic and international standards, the French design concept, and construction requirements of China, etc. For example, in terms of the enclosure structure in the core area of the laboratory, the construction team has repeatedly tested and replaced the traditional glue sealing method with advanced laser welding, which has better airtightness and durability. The P4 team owns the independent intellectual property rights of the technology. Also, self-designed automatic control mathematical model achieves a more stable differential pressure control effect.

In January 2017, Wuhan P4 Laboratory obtained the laboratory accreditation qualification granted by the National Accreditation Commission. In August of the same year, it obtained the National Health and Planning Commission’s activity license and became China’s first P4 laboratory officially to put into operation, marking China’s the ability and conditions of high-level pathogenic microorganism experimental activities. As an important part of the national high-level biosecurity laboratory system, the laboratory will become an important part of China’s public health defense system and a technical platform for infectious disease prevention and control research at home and abroad. At present, the Zhengdian laboratory team is mainly dedicated to the operation and maintenance of the laboratory, providing irreplaceable conditions and system services for scientists to carry out biosafety research.

General Secretary Xi Jinping pointed out that P4 laboratory construction is very important for China’s public health. The Wuhan Institute of Virology will focus on the “first action” plan of the Chinese Academy of Sciences, rely on the Wuhan P4 laboratory cluster platform, and combine the advantages of the inside and outside of the hospital, according to the goal and mechanism of biological safety the National Laboratory, to build a large scientific research center of biosecurity of the Chinese Academy of Sciences.

The team of Zhengdian Lab has only 28 people.

Song Donglin, deputy director of Wuhan P4 Laboratory and party member of Zhengdian Laboratory, is the core backbone of the biosecurity system.

Tong Xiao, Secretary of the Party Branch of Zhengdian Laboratory, is the technical person in charge of the construction of Wuhan P4 Laboratory and the chief commander of the project.

The party branch of Zhengdian Laboratory currently has 16 party members, accounting for 57% of the total number of laboratory construction teams. In the Zhengdian laboratory construction team, there are 7 deputy senior and above personnel, all of whom are members of the Communist Party of China.

Let’s try to see if we can dig out the 16 party members in the Zhengdian laboratory.

We have a list of party branches of Wuhan Institute of Virology in 2013.

General Party Branch and Party Branch of Wuhan Institute of Virology of Chinese Academy of Sciences

The specific list of the (General) Party Branch Committees is as follows (sorted by surname strokes of Chinese Character):

(1) General Party Branch of Research

General Secretary of the Branch: Sun Xiulian

Members of the General branch: Li Feng, Zhang Bo, Peng Ke

The four Party branches under the General Party Branch of the Research, namely:

1. Party Branch of Microbiological Resources and Bioinformatics Research Center

  • Secretary: Sun Xiulian
  • Deputy Secretary: Hu Xiaomin
  • Organizing Commissioner and Discipline Inspection Commissioner: Chen Jianjun
  • Propaganda Commissioner: Tang Shuang

2. Party Branch of the Emerging Infectious Disease Research Center

  • Secretary: Zhang Bo
  • Deputy Secretary: Hu Yangbo
  • Organizing Commissioner and Discipline Inspection Commissioner: Zheng Zhenhua
  • Propaganda Commissioner: Liu Qiaojie

3. Party Branch of Molecular Virus and Pathology Research Center

  • Secretary: Peng Ke
  • Deputy Secretary: Qiu Yang
  • Organizing Commissioner and Discipline Inspection Commissioner: Wang Suyun
  • Propaganda Commissioner: Zhang Haiwei

4. Party Branch of Analytical Microbiology and Nanobiology Research Center

  • Secretary: Li Feng
  • Organizing Commissioner and Discipline Inspection Commissioner: Zhou Juan
  • Propaganda Commissioner: Zhang Xiaowei

(2) General Party Branch of the Comprehensive management

  • Secretary of the General Branch: Li Liping
  • Members of the General Branch: Liu Jinxue, Tong Xiao
  • There are three Party branches under the General Party Branch of the Comprehensive management, namely:

1. Party Branch of Core Division

  • Secretary: Li Liping
  • Deputy Secretary: Li Li
  • Organizing Commissioner: Han Zhaoju
  • Discipline Inspection Commissioner: Hu Yan
  • Propaganda Committee: Chen Tudou

2. Party Branch of Support

  • Secretary: Liu Jinxue
  • Organizing Commissioner and Discipline Inspection Commissioner: Du Anna
  • Propaganda Commissioner: Si Jiali

3. Party Branch of Zhengdian Laboratory

  • Secretary: Tong Xiao
  • Organizing Commissioner and Discipline Inspection Commissioner: Xie Weiwei
  • Propaganda Commissioner: Wu Xiaowu

(3) General Party Branch of the Retired

  • Secretary of the General Branch: Yang Fusheng
  • Members of General branch: Ding Qingquan, Sun Xiuzhen

1. First Retired Branch

  • Secretary: Sun Xiuzhen
  • Deputy Secretary: Yang Baoyu
  • Organizing Commissioner: Yang Fusheng
  • Discipline Inspection Commissioner: Liu Minghui
  • Propaganda Commissioner: Deng Hong

2. Second Retired Branch

  • Secretary: Ding Qingquan
  • Deputy Secretary: Zhang Zhongxin
  • Organizing Commissioner: Peng Yongqing
  • Discipline Inspection Commissioner: Ma Guohua
  • Propaganda Commissioner: Hu Xianrong

(4) General Party Branch of Graduate Students

  • Secretary of the General Branch: Wang Yanfei

Members of the General branch: Zhou Kun, Hu Xiao, Tang Jielin, Chang Meng, Pei Pingping

There are 5 Party branches under the General Party Branch of Graduate Students, namely:

1. Graduate Party Branch of the Research Center for Microbial Resources and Bioinformatics

  • Secretary: Chang Meng
  • Deputy Secretary: Wang Jia
  • Organizing Commissioner and Discipline Inspection Commissioner: Wu Zhongqiang
  • Propaganda Commissioner: He Lihong

2. Graduate Party Branch of Emerging Infectious Disease Research Center

  • Secretary: Hu Xiao
  • Deputy Secretary: Yang Jieyu
  • Organizing Commissioner: Gao Xinyu
  • Discipline Inspection Commissioner: Huang Shaojia
  • Propaganda Commissioner: Shen Xurui

3. Graduate Party Branch of Molecular Virus and Pathology Research Center

  • Secretary: Jielin Tang
  • Deputy Secretary: Hu Huimin
  • Organizing Commissioner: Wang Xianzhang
  • Discipline Inspection Commissioner: Zhang Shumin
  • Propaganda Commissioner: Wang Qingxing

4. Graduate Party Branch of Analytical Microbiology and Nanobiology Research Center

  • Secretary: Zhou Kun
  • Organizing Commissioner and Discipline Inspection Commissioner: Gao Jiawang
  • Propaganda Commissioner: Yang Mengsi

5. Party Branch of Freshman

  • Secretary: Pei Pingping
  • The Ninth Committee of Wuhan Institute of Virology, Chinese Academy of Sciences

Release time: Apr. 25, 2019

  • Secretary: Xiao Gengfu
  • Deputy Secretary: He Changcai

Members (sorted by strokes of surname of Chinese Characters):

Guan Wuxiang, Sun Xiulian, Li Liping, Xiao Gengfu, He Changcai, Cui Zongqiang, Tong Xiao

The people in this list are the lineal members of the Wuhan Institute of Virology, or the guardians of security and politics. What can be determined here is that Tong Xiao is the head of the Party branch of the Zhengdian laboratory, which is the P4 laboratory. Xiao Gengfu, one of Tian Bo ’s students, was the secretary of the Wuhan Institute of Virology. At the same time, Wang Yanyi, another student of Tian Bo, was the director of the Wuhan Institute of Virology.

Through the above dig, we have understood the stories of the two laboratories of Wuhan Virus Research Institute. The main body of the virus research laboratory or the body that the Wuhan Institute of Virology can use is the building built on April 12, 2004 that mentioned in the dig materials above – the Xiaohongshan New Park of the Wuhan Institute of Virology, namely, the P3 laboratory, which is the National Key Laboratory of Virology. But the Zhengdian’s laboratory building, where only 28 people can enter, is a real P4 laboratory.

According to the expose of Mr. Miles Guo, there is a real P4 laboratory in the underground of the P4 laboratory building, so can these 28 people enter the underground? Who is the user of the underground laboratory?

The answer is for sure that those 28 people cannot enter the underground part. They are only the guardians or cover-ups of the underground part. In fact, the truth is not difficult to find, as long as the United States goes to check the equipment supply list of the supply company, and then check the records of major equipment and facilities of the Wuhan Institute of Virology against the list. The user in the underground is an army team composed of the Military Medical Academy of PLA. The Military Medical Academy is affiliated to the General Logistics Department of PLA. In 2016, the General Logistics Department of PLA was abolished and the Logistics Support Department of the Central Military Commission was established. The Military Medical Academy was transferred to the Logistics Support Department of the Central Military Commission but was still ranked as Corps Commander-level, which is the highest ranking in the PLA. The Logistics Support Department of the Central Military Commission, is the first-level functional department of the Central Military Commission, deputy theater level, and is responsible for the logistics support of the entire military.

Chen Wei (February 1966-), a native of Lanxi, Zhejiang, a preventive medical scientist and a biological defense expert of the People’s Republic of China, a major general of the Chinese People’s Liberation Army, and an academician of China Engineering Academy, and delegate of the 12th National People’s Congress and members of the 13th CPPCC National Committee. She has long been engaged in research on biohazard prevention and control, and is particularly committed to the research and development of new vaccines and therapeutic drugs for highly pathogenic microorganisms. She once rendered meritorious contributions of 2nd and 3rd grade in the PLA, each twice.

From 2001 to 2004, she worked as a postdoctoral fellow at the Institute of Bioengineering, Academy of Military Medical Sciences. She was unusually promoted to a researcher (senior professional title) in 2002 and became a doctoral supervisor in 2003. In 2012, she was promoted from the deputy director of the Institute of Microbiology and Epidemiology to the Director of the Institute of Bioengineering. In July 2015, she was promoted to the rank of major general of the Chinese People’s Liberation Army. In 2019, she was elected as an academician of the Chinese Academy of Engineering. She was a representative of the 12th National People’s Congress and a member of the 13th National Committee of the Chinese People’s Political Consultative Conference.

The most important thing is that Chen Wei is the core person of the genotype Ebola virus vaccine research and development team in 2014. However, the scientist of the Chinese Academy of Sciences who has made outstanding contributions in the field of Ebola virus is Academician Gao Fu, who serves for the Institute of Microbiology of the Chinese Academy of Sciences, the place where his promoter and introducer Academician Tian Bo also served. And the Ebola virus used by Chen Wei to study the vaccine lies quietly in the Wuhan Institute of Virology. So, here comes a question. Where is the P4 laboratory that Major General Chen Wei used to study the Ebola virus? Because in 2014, the P4 Laboratory in Zhengdian has not yet been completed. DT will leave it to readers to dig and brainstorm.

Foresight and perseverance Innovation and breakthrough – Interview with Chen Wei, the leader of the genotype Ebola vaccine R & D team Author Qu Mingming 2017 Birth of the world’s first approved new drug of Ebola vaccine Author Gan Xiao Oct. 29, 2017

It is obvious that the key to the door of the P4 laboratory is in the hands of the Chinese People’s Liberation Army.

Let the two stories wind down here. Next part to be continued.

Edited by 【Himalaya Hawk Squad】

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